Evidence map›Paper›PMID 41410864›Full record

ArticleJournal of general internal medicine2025

Development of a Mortality Prediction Model for Incarcerated Adults to Identify Palliative Care Needs.

W James Deardorff, Alexandra K Lee, Kaiwei Lu, Bocheng Jing, W John Boscardin, Michele DiTomas, John Dunlap, Brie A Williams, Sei J Lee, Alexander K Smith

Abstract read
In one paragraph

Article in Journal of general internal medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

W James DeardorffDivision of Geriatrics, University of California, San Francisco, San Francisco, CA, USA. william.deardorff@ucsf.edu.ORCID http://orcid.org/0000-0002-7947-3008
Alexandra K LeeDivision of Geriatrics, University of California, San Francisco, San Francisco, CA, USA.
Kaiwei LuDivision of Geriatrics, University of California, San Francisco, San Francisco, CA, USA.
Bocheng JingDivision of Geriatrics, University of California, San Francisco, San Francisco, CA, USA.
W John BoscardinDivision of Geriatrics, University of California, San Francisco, San Francisco, CA, USA.
Michele DiTomasCalifornia Department of Corrections and Rehabilitation, Elk Grove, CA, USA.
John DunlapCalifornia Department of Corrections and Rehabilitation, Elk Grove, CA, USA.
Brie A WilliamsDivision of Health and Society, University of California, San Francisco, San Francisco, CA, USA.
Sei J LeeDivision of Geriatrics, University of California, San Francisco, San Francisco, CA, USA.
Alexander K SmithDivision of Geriatrics, University of California, San Francisco, San Francisco, CA, USA.

Funding

VARC CoreP30AG044281 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Louise C. Walter · 2013 to 2026
$19.9M
Institutional Career Development Core SupplementKL2TR001870 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KANAYA, ALKA M., SARKAR, URMIMALA · 2016 to 2025
$19.7M
Improving Medical Decision Making for Older Patients with End Stage Renal DiseaseR01AG066892 · NIA · TUFTS MEDICAL CENTER · PI PAASCHE-ORLOW, MICHAEL, VOLANDES, ANGELO · 2020 to 2025
$10.8M
Advancing Health Disparities Research in Aging: The Aging Research in Criminal Justice & Health (ARCH) NetworkR24AG065175 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LISA C BARRY, BRIE A WILLIAMS · 2019 to 2026
$3.3M
Prognostic Indices for Hospitalized Older Adults with and without Alzheimer’s Disease and Related DementiasR01AG079982 · NIA · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI Sei Lee, Alexander Keliimoeanu Smith · 2023 to 2026
$3.1M
Mentoring Researchers in Prognosis Research in Alzheimer’s Disease and Related DementiasK24AG068312 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Alexander Keliimoeanu Smith · 2020 to 2026
$1.2M
Mentoring Patient-Oriented Research to Individualize Care for Hospitalized Older Adults with and without Alzheimer's Disease and Related DementiasK24AG066998 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Sei Lee · 2021 to 2026
$1.1M
Contributions of Hypoglycemia and Hyperglycemia to Adverse Geriatric Outcomes in NH Residents with Diabetes and Alzheimer's Disease and Related Dementias (ADRD)K01AG073532 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LEE, ALEXANDRA KATHRYN · 2021 to 2025
$714k
Enhancing prognosis communication for older adults in skilled nursing facilitiesK76AG094730 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI William James Deardorff · 2025 to 2026
$480k
A comprehensive prognostic model for older adults discharged to skilled nursing facilities.R03AG082859 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DEARDORFF, WILLIAM JAMES · 2023 to 2024
$323k
NCATS NIH HHS KL2 TR001870NCATS NIH HHS KL2TR001870NIA NIH HHS K01 AG073532NIA NIH HHS K01AG073532NIA NIH HHS K24 AG066998NIA NIH HHS K24AG066998NIA NIH HHS K24 AG068312NIA NIH HHS K24AG068312NIA NIH HHS K76 AG094730NIA NIH HHS K76AG094730NIA NIH HHS P30 AG044281NIA NIH HHS P30AG044281NIA NIH HHS R01 AG066892NIA NIH HHS R01 AG079982NIA NIH HHS R01AG079982NIA NIH HHS R03 AG082859NIA NIH HHS R03AG082859NIA NIH HHS R24 AG065175NIA NIH HHS R24AG065175
6 · The paper itself

Abstract

backgroundEstimating mortality risk in incarcerated adults is important for identifying individuals who may benefit from palliative care and compassionate release referrals.

objectiveTo develop and internally validate a 2-year mortality prediction model in incarcerated adults.

designCohort study (February 1, 2018-February 1, 2020).

participantsIncarcerated adults aged ≥ 18 years residing at a California Department of Corrections and Rehabilitation (CDCR) prison for ≥ 1 year. MAIN MEASURES: Model predictors included demographics (e.g., age, sex), housing status (general housing vs. higher acuity infirmary bed vs. lower acuity infirmary bed), functional assessment (level of mobility restriction), healthcare utilization (e.g., hospitalizations and intensive care unit admissions in the previous year), and chronic conditions. The primary outcome was natural death at 2 years, defined as death due to causes other than suicide, homicide, accidental injury, or drug overdose. Cox proportional hazards regression with LASSO for variable selection was used to develop the model. Model performance was assessed by discrimination (area under the receiver operating characteristic curve (AUC) at 2 years) and calibration (plots of predicted and observed mortality). Classification metrics were assessed at clinically relevant thresholds. KEY

resultsThe final cohort included 89,430 adults (median age 40 years (interquartile range = 20), 10.2% ≥ 60 years, 30.6% Black, 41.4% Hispanic). At 2 years, 506 (0.6%) individuals experienced a natural death. The optimism-corrected AUC at 2 years after bootstrap internal validation was 0.926 (95% confidence interval (CI) = 0.915-0.938). The calibration plot at 2 years suggested good calibration. At a 2-year mortality risk threshold of 5%, sensitivity, specificity, and positive predictive value were 47.6% (95% CI = 42.3-51.6%), 98.4% (95% CI = 98.2-98.4%), and 16.7% (95% CI = 14.3-18.5%), respectively.

conclusionsThe mortality risk estimates from this model can help clinicians identify individuals who may most benefit from advance care planning discussions, palliative care services, and compassionate release referrals.

Indexed as

compassionate releaseincarcerationmortalitypalliative careprognostic model

Identifiers

PMID41410864
PMCPMC13075380

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.