Evidence mapPaperPMID 41413752Full record

ReviewDiscover oncology2025

The clinical significance of circulating microRNAs as biomarkers in lung cancer diagnosis and prognosis.

Jun Fan, DongMing Shen, Lei He, ChunXia Yan, Hu Li, Yebiao Zhang, XiaoSong Bai

Abstract readReview
In one paragraph

Review in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jun Fan *Department of Laboratory, Luodian Hospital, Baoshan District, Shanghai, 201908, China.
DongMing Shen *Department of Laboratory, Luodian Hospital, Baoshan District, Shanghai, 201908, China.
Lei He *Department of Laboratory, Luodian Hospital, Baoshan District, Shanghai, 201908, China.
ChunXia YanDepartment of Laboratory, Luodian Hospital, Baoshan District, Shanghai, 201908, China.
Hu LiDepartment of Laboratory, Luodian Hospital, Baoshan District, Shanghai, 201908, China.
Yebiao ZhangDepartment of Laboratory, Luodian Hospital, Baoshan District, Shanghai, 201908, China.
XiaoSong BaiDepartment of Laboratory, Luodian Hospital, Baoshan District, Shanghai, 201908, China. baixiaosong68@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung cancer continues to be a major cause of deaths associated with cancer, with a considerable number of patients being diagnosed at more advanced stages of the disease. Circulating microRNAs (miRNAs), which are stable in body fluids, offer promising avenues for non-invasive biomarker identification. Recent advancements have highlighted the utility of specific miRNA signatures in treatment decisions and prognostic evaluations. This review has explored the significant function of circulating miRNAs as promising diagnostic and prognostic biomarkers for lung cancer. Integration of miRNA profiles with clinical parameters has shown potential in predicting treatment responses and patient outcomes. Nevertheless, obstacles persist in standardizing the protocols for isolating and quantifying miRNAs, along with the variability of miRNA expression across various cancer types and stages. Future research focusing on larger, multi-center studies is essential to validate the diagnostic and prognostic capacities of circulating miRNAs and enhance their applicability in clinical practice.

Indexed as

Circulating miRNADiagnosisLiquid biopsiesLung cancerPrognosis

Identifiers

PMID41413752
PMCPMC12830539

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.