ArticleRenal failure2025
Effect of exercise on nutrition, inflammation, muscle health and cardio-cerebrovascular events in maintenance hemodialysis patients: a real-world prospective cohort study.
Article in Renal failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Prevalence and influencing factors of malnutrition in maintenance hemodialysis patients in China: a systematic review.Frontiers in public health · 2026Pooled it
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Maintenance hemodialysis (MHD) patients face high risks of malnutrition-inflammation complex syndrome, muscle atrophy, and cardio-cerebrovascular events (CCVE). These challenges have led to increasing attention on the importance of exercise for MHD patients' health. This prospective study evaluated the impact of daily physical activity (PA) on multidimensional health outcomes in this population. A total of 307 MHD patients were enrolled and divided into three groups based on their daily PA levels according to the Physical Activity Rating Scale: inactive (Group A), low PA (Group B), and moderate-to-high PA (Group C). A follow-up and comparison of differences in nutrition, inflammation, muscle health, and the occurrence of CCVE were conducted among the three groups before and after the study. At baseline, patients in group C had better malnutrition-inflammation scores, calf circumference, handgrip strength, Ishii scores, prealbumin, and albumin than the other two groups. After 11.9 ± 0.25 months of follow-up, all the aforementioned indicators deteriorated to varying degrees in Groups A and B, whereas Group C showed no significant deterioration. Furthermore, Group C showed improvements in mid-arm muscle circumference and transferrin. During the follow-up period, 52 patients experienced CCVE. Both Kaplan-Meier survival analysis and multivariate Cox regression analysis revealed that active exercise was associated with reduced risk of CCVE occurrence, particularly in patients undergoing dialysis for one to five years or those with comorbid diabetes. In conclusion, active exercise is associated with improvements in malnutrition, inflammation, and muscle health while potentially reducing the risk of CCVE in MHD patients.
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