Evidence map›Paper›PMID 41414913›Full record

ArticleAnimal models and experimental medicine2025

ZSF1 lean rats - How healthy are they?

Antje Schauer, Beatrice Vahle, Volker Adams, Axel Linke, Antje Augstein

Abstract read
In one paragraph

Article in Animal models and experimental medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. ZSF1 lean rats - How healthy are they?Animal models and experimental medicine · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Antje SchauerDepartment of Internal Medicine and Cardiology, Heart Center Dresden - Laboratory of Molecular and Experimental Cardiology, Technische Universität Dresden, Dresden, Germany.ORCID 0000-0003-0003-6882
Beatrice VahleDepartment of Internal Medicine and Cardiology, Heart Center Dresden - Laboratory of Molecular and Experimental Cardiology, Technische Universität Dresden, Dresden, Germany.
Volker AdamsDepartment of Internal Medicine and Cardiology, Heart Center Dresden - Laboratory of Molecular and Experimental Cardiology, Technische Universität Dresden, Dresden, Germany.
Axel LinkeDepartment of Internal Medicine and Cardiology, Heart Center Dresden - Laboratory of Molecular and Experimental Cardiology, Technische Universität Dresden, Dresden, Germany.
Antje AugsteinDepartment of Internal Medicine and Cardiology, Heart Center Dresden - Laboratory of Molecular and Experimental Cardiology, Technische Universität Dresden, Dresden, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ZSF1 lean rats are widely used as controls in cardiometabolic studies involving ZSF1 obese rats, which develop a cardiometabolic syndrome and diastolic dysfunction at a young age due to a double leptin receptor mutation (Lepr

Indexed as

AnimalsBlood PressureBody WeightFemaleMitochondriaMuscle, SkeletalRatsRats, WistarReceptors, LeptinReceptors, Leptincardiovascular functionHFpEFHFpEF rat modelskeletal muscle functionZSF1 lean rat

Identifiers

PMID41414913
PMCPMC12884432

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.