Evidence mapPaperPMID 41415469Full record

ArticlebioRxiv : the preprint server for biology2025

BCL-X

Tupa Basuroy, Treg Grubb, Ananthan Sadagopan, Xingping Qin, Kylee Madison, Autumn Hall, Belinda Willard, Sakari Vanharanta, Kristopher A Sarosiek, Srinivas R Viswanathan and 1 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Tupa BasuroyDepartment of Cancer Sciences, Cleveland Clinic Research, Cleveland Clinic, Cleveland, OH USA.
Treg GrubbDepartment of Cancer Sciences, Cleveland Clinic Research, Cleveland Clinic, Cleveland, OH USA.
Ananthan SadagopanDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.ORCID 0000-0001-6306-4907
Xingping QinJohn B. Little Center for Radiation Sciences, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Kylee MadisonDepartment of Cancer Sciences, Cleveland Clinic Research, Cleveland Clinic, Cleveland, OH USA.
Autumn HallProteomics and Metabolomics Core, Cleveland Clinic, Cleveland, OH, USA.
Belinda WillardProteomics and Metabolomics Core, Cleveland Clinic, Cleveland, OH, USA.
Sakari VanharantaTranslational Cancer Medicine Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.ORCID 0000-0001-5619-7963
Kristopher A SarosiekDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Srinivas R ViswanathanDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.ORCID 0000-0003-1856-3023
Abhishek A ChakrabortyDepartment of Cancer Sciences, Cleveland Clinic Research, Cleveland Clinic, Cleveland, OH USA.

Funding

Developmental regulation of apoptosis as a modifiable driver of radiotherapy-induced neurocognitive impairment in pediatric patientsR37CA248565 · NCI · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Kristopher Andrew Sarosiek · 2020 to 2026
$2.6M
Identifying targetable apoptotic vulnerabilities for the treatment of AL amyloidosisR01DK125263 · NIDDK · HARVARD SCHOOL OF PUBLIC HEALTH · PI SAROSIEK, KRISTOPHER ANDREW · 2020 to 2023
$1.4M
NCI NIH HHS R37 CA248565NIDDK NIH HHS R01 DK125263
6 · The paper itself

Abstract

The BCL-X

Identifiers

PMID41415469
PMCPMC12710959

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.