ArticleFrontiers in nutrition2025
Association between live microbe intake and depression in COPD aged 40 years and older: evidence from NHANES 2005-2018.
Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This study aimed to investigate the association between dietary intake of live microbes and the prevalence of depression among patients with Chronic Obstructive Pulmonary Disease (COPD) aged 40 years and older, using data from the National Health and Nutrition Examination Survey (NHANES) 2005-2018. Methods: The study included 1,494 participants (representing 9.04 million COPD adults in the U.S.) aged 40 and above. Dietary intake of live microbes was categorized into low, moderate, and high groups based on 24-h dietary recall data. Depression was assessed using the Patient Health Questionnaire-9 (PHQ-9) with a score ≥10 indicating depression. Weighted logistic regression analysis was performed to evaluate the association between live microbe intake and depression, adjusting for various covariates. Additionally, subgroup analysis and sensitivity analysis were conducted. Results: Higher dietary intake of live microbes was associated with a lower prevalence of depression in COPD participants. In the fully adjusted model, compared to the low intake group, the odds ratio (OR) for depression was 0.55 (95% CI: 0.33-0.92) for the high intake group. This inverse association was still statistically significant in individuals under 65 years, males, non-obese individuals, and those without cardiovascular disease. In addition, the results of the sensitivity analysis also indicate relationship stability. Conclusion: This study indicates an inverse association between higher dietary intake of live microbes and the prevalence of depression among COPD patients aged 40 and above in the United States. Future prospective studies are needed to verify this association and explore underlying mechanisms.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.