Trial reportEuropean journal of applied physiology2026
Acute arterial stiffness responses to various bouts of grounded and heightened one-leg standing.
Trial report in European journal of applied physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed.
- Association of composite inflammatory indicators with osteoporosis and sarcopenia in type 2 diabetes mellitus: the mediating role of inflammation.Journal of endocrinological investigation · 2026Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
objectiveTo examine acute effects of various bouts of grounded and heightened one-leg standing (OLS) on arterial stiffness of supporting and non-supporting side, and to investigate the possible role of muscle activity of supporting leg.
methodsTwenty-two healthy young adults (24.3 ± 0.3 years) underwent 7 conditions using random crossover fashion: no-intervention control (CON), grounded OLS for 1 × 3 min (G1), 2 × 3 min (G2) and 3 × 3 min (G3), and heightened OLS for 1 × 3 min (H1), 2 × 3 min (H2) and 3 × 3 min (H3). Bilateral arterial stiffness measurements using cardio-ankle vascular index (CAVI) were performed at baseline (BL), immediately (0 min) and every 10 min after OLS. CAVI changes from BL in the same condition (∆CAVI) were analyzed. Root mean square (RMS) from electromyography was used to reflect gastrocnemius muscle (GS) activity.
resultsAs to supporting side, ∆CAVI remained unchanged in G1, G2 and G3, and decreased in H1 with - 0.4 ± 0.1 and in H2 with - 0.5 ± 0.1 relative to CON at 0 min; however, it increased in H3 with 0.5 ± 0.1 relative to CON at 0 min. ∆CAVI changes of non-supporting side were similar to those of supporting side in all corresponding conditions. RMS of GS from supporting leg was increased in heightened OLS (P < 0.01).
conclusionGrounded OLS has no impacts on AS regardless of standing dose, and heightened OLS results in AS decrease and increase with increasing standing bouts. AS changes induced by height exposure are bilateral, and might be related to increased GS activity of supporting leg.
Indexed as
Identifiers
41417062What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.