Evidence map›Paper›PMID 41417065›Full record

ArticleEuropean journal of applied physiology2026

Effects of running-induced fatigue on ankle plantar-dorsiflexion performance and functional connectivity in brain and brain-muscle networks.

Jianglong Zhan, Changxiao Yu, Chuyi Zhang, Songlin Xiao, Bin Shen, Zhen Xu, Weijie Fu

Abstract read
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In one paragraph

Article in European journal of applied physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jianglong ZhanKey Laboratory of Exercise and Health Sciences of Ministry of Education, School of Exercise and Health, Shanghai University of Sport, Shanghai, 200438, China.
Changxiao YuKey Laboratory of Exercise and Health Sciences of Ministry of Education, School of Exercise and Health, Shanghai University of Sport, Shanghai, 200438, China.
Chuyi ZhangKey Laboratory of Exercise and Health Sciences of Ministry of Education, School of Exercise and Health, Shanghai University of Sport, Shanghai, 200438, China.
Songlin XiaoKey Laboratory of Exercise and Health Sciences of Ministry of Education, School of Exercise and Health, Shanghai University of Sport, Shanghai, 200438, China.
Bin ShenKey Laboratory of Exercise and Health Sciences of Ministry of Education, School of Exercise and Health, Shanghai University of Sport, Shanghai, 200438, China.
Zhen XuKey Laboratory of Exercise and Health Sciences of Ministry of Education, School of Exercise and Health, Shanghai University of Sport, Shanghai, 200438, China.
Weijie FuSchool of Intelligent Sports Engineering, Shanghai University of Sport, Shanghai, 200438, China. fuweijie@sus.edu.cn.ORCID http://orcid.org/0000-0002-7552-0452

Funding

National Natural Science Foundation of China 12272238
6 · The paper itself

Abstract

purposeThis study investigated the effects of running-induced fatigue on ankle plantar-dorsiflexion performance and explored the underlying neuromuscular control mechanisms.

methodsTwenty-four male participants performed a right-sided ankle plantar-dorsiflexion task before and after running-induced fatigue, with simultaneous recordings of ankle peak torque, electroencephalography signals from the primary motor cortex (M1; Cz, C1, C2) and other brain regions, and electromyography signals from the tibialis anterior (TA) and medial gastrocnemius (MG). Ankle peak torque was used to assess plantar-dorsiflexion performance. Beta- and gamma-band corticocortical coherence (CCC) was used to evaluate brain network connectivity, while partial directed coherence (PDC) was applied to analyze the brain-muscle network.

resultsIn the brain network, fatigue significantly reduced beta-band CCC for C1-Cz electrode pair (p = 0.022) during dorsiflexion, beta band for C2-Cz (p = 0.014), and gamma band for C1-Cz (p = 0.003) during plantarflexion. In the brain-muscle network, fatigue significantly decreased gamma-band PDC for TA-Cz (p = 0.007) during dorsiflexion and for MG-Cz (p = 0.010) during plantarflexion in the ascending pathway. The declines in ankle peak torques after fatigue were positively correlated with reduced gamma-band PDC in the ascending pathway (p < 0.034).

conclusionThese findings suggest that running-induced fatigue significantly reduced functional connectivity within bilateral M1 regions and the ascending pathway of the brain-muscle network during unilateral ankle plantar-dorsiflexion, with weakened connectivity in the ascending pathway linked to decreased ankle force output.

Indexed as

AnkleMuscle FatigueMuscle, SkeletalRunningAdultElectromyographyHumansMaleMotor CortexBrain–muscle networkBrain networkCoherence analysisExercise-induced fatigueFunctional connectivity

Identifiers

PMID41417065

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.