Evidence map›Paper›PMID 41417214›Full record

ReviewDermatology and therapy2026

Clinical Implications of the Skin Microbiota in the Therapy of Cutaneous T Cell Lymphoma: A Scoping Review.

Sonia Czyz, Joshua Quan, Kerry Yang, Raed Alhusayen, Jori Hardin

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Dermatology and therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sonia CzyzDepartment of Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Joshua QuanDepartment of Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Kerry YangDepartment of Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Raed AlhusayenDivision of Dermatology, Department of Medicine, Sunnybrook General Hospital, University of Toronto, Toronto, ON, Canada.
Jori HardinDivision of Dermatology, Department of Medicine, University of Calgary, Calgary, AB, Canada. jori.hardin@albertahealthservices.ca.ORCID http://orcid.org/0000-0002-3419-5550

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cutaneous T cell lymphomas (CTCL) are non-Hodgkin T cell malignancies defined by malignant T cell transformation and accumulation in the skin. Limited understanding of CTCL pathogenesis, including the role of the tumor microenvironment, hinders effective treatment. Emerging evidence implicates the skin microbiota as a key modulator of disease, with microbial dysbiosis contributing to progression and representing a novel therapeutic target. This review synthesizes findings from 37 rigorously selected studies, outlining current knowledge of the CTCL-associated microbiome, mycobiome, and virome. It evaluates therapeutic strategies aimed at microbial colonization, emphasizing the potential of modulating host-microbe interactions. Additionally, we provide comprehensive clinical insight into the indications for microbial-modulating strategies of the microbiota in CTCL.

Indexed as

AntibioticsAntifungalAntiviralCutaneous T cell lymphomaMicrobiomeMicrobiotaMycosis fungoidesSezary syndrome

Identifiers

PMID41417214
PMCPMC12936262

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.