Evidence map›Paper›PMID 41417899›Full record

ArticleScience advances2025

Unconventional CD8

Shanelle P Reilly, Madison L Smith, Samantha M Borys, Céline Fugère, Delia Demers, Michael J Hogan, David Zemmour, Laurent Brossay

Abstract read
In one paragraph

Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. HLA-E-restricted SARS-CoV-2 epitopes drive CD8Journal of translational medicine · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shanelle P ReillyDepartment of Molecular Microbiology and Immunology, Division of Biology and Medicine, Brown University, Providence, RI 02906, USA.ORCID 0000-0001-9465-706X
Madison L SmithDepartment of Molecular Microbiology and Immunology, Division of Biology and Medicine, Brown University, Providence, RI 02906, USA.ORCID 0009-0000-4651-4777
Samantha M BorysDepartment of Molecular Microbiology and Immunology, Division of Biology and Medicine, Brown University, Providence, RI 02906, USA.ORCID 0000-0003-4960-131X
Céline FugèreDepartment of Molecular Microbiology and Immunology, Division of Biology and Medicine, Brown University, Providence, RI 02906, USA.
Delia DemersDepartment of Molecular Microbiology and Immunology, Division of Biology and Medicine, Brown University, Providence, RI 02906, USA.
Michael J HoganDepartment of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0002-6244-2993
David ZemmourDepartment of Pathology, University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0002-0990-217X
Laurent BrossayDepartment of Molecular Microbiology and Immunology, Division of Biology and Medicine, Brown University, Providence, RI 02906, USA.ORCID 0000-0002-7497-8488

Funding

ImmGen: Gene Expression and Regulation in Immune CellsR24AI072073 · NIAID · JOSLIN DIABETES CENTER · PI CHRISTOPHE O. BENOIST · 2007 to 2026
$28.5M
NK T Cell Interactions with NK Cells During Viral InfectionR01AI046709 · NIAID · BROWN UNIVERSITY · PI BROSSAY, LAURENT · 2001 to 2022
$8.0M
Brown Respiratory Research Training ProgramT32HL134625 · NHLBI · BROWN UNIVERSITY · PI Elizabeth O Harrington, Sharon Irene Smith Rounds · 2017 to 2026
$5.1M
Immune response to MCMV infection in the salivary glandsR01AI173163 · NIAID · BROWN UNIVERSITY · PI Laurent Brossay · 2023 to 2026
$3.2M
PD-1 Mediated Regulation of Salivary Gland IntegrityF31DE032593 · NIDCR · BROWN UNIVERSITY · PI BORYS, SAMANTHA · 2023 to 2025
$136k
NHLBI NIH HHS T32 HL134625NIAID NIH HHS R01 AI046709NIAID NIH HHS R01 AI173163NIAID NIH HHS R24 AI072073NIDCR NIH HHS F31 DE032593
6 · The paper itself

Abstract

Nonclassical CD8

Indexed as

CD8-Positive T-LymphocytesCytomegalovirusCytomegalovirus InfectionsEpitopes, T-LymphocyteHistocompatibility Antigens Class IAnimalsHLA-E AntigensHumansMiceMuromegalovirusEpitopes, T-LymphocyteHistocompatibility Antigens Class IHLA-E AntigensQ surface antigens

Identifiers

PMID41417899
PMCPMC12716397

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.