ArticleAmerican journal of physiology. Endocrinology and metabolism2026
Nr4a1 β-cell specific deletion impairs glucose tolerance in female mice.
Article in American journal of physiology. Endocrinology and metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
The Nr4a family of transcription factors controls the expression of genes essential for fuel metabolism and cellular proliferation. The loss of Nr4a1 in the 832/13 INS-1 β-cell line diminishes mitochondrial respiration, decreases ATP production, and impairs glucose-stimulated insulin secretion. Nr4a1 overexpression increases β-cell proliferation, and full-body Nr4a1 knockout mice have decreased β-cell area. Thus, we hypothesize that β-cell Nr4a1 expression plays a critical role in diabetes disease progression. Here we report the effects of β-cell specific
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.