ArticleBMC genomics2025
Assembly and comparative analysis of the complete mitochondrial and chloroplast genomes of the medicinal plant Vincetoxicum Pycnostelma.
Article in BMC genomics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVincetoxicum pycnostelma is a plant with pharmaceutical importance in traditional Chinese medicine, because its roots and rhizomes contain abundant anti-tumor and anti-inflammatory active compounds. Although sequencing its organelle genomes is critical to understand the genetic basis of these medicinal traits and advance molecular breeding programs, the mitochondrial genome (mtDNA) of V. pycnostelma has not yet been reported.
resultsHere, we sequenced and assembled the organelle genomes of V. pycnostelma with PacBio and BGI sequencing technologies, and conducted a comprehensive comparative genomic analysis. The complete mtDNA (703,719 bp, GC content 43.98%) encoded 38 protein-coding genes (PCGs), 18 tRNAs, and 3 rRNAs, whereas the chloroplast genome (cpDNA; 159,426 bp, GC content 37.85%) contained 79 PCGs, 29 tRNAs, and 4 rRNAs. Codon usage analysis indicated that both the mtDNA and cpDNA exhibited conserved codon usage preferences. Additionally, both genomes contained abundant microsatellite, tandem, and dispersed repeat sequences, and cpDNA showed a more concentrated distribution of repeats. We identified 59 homologous fragments between the mtDNA and cpDNA of V. pycnostelma, including 16 complete PCGs and 5 complete tRNA genes. Phylogenetic analysis and collinearity assessments demonstrated that V. pycnostelma exhibited the closest genetic affinity to Asclepias syriaca. A comparative analysis of nucleotide diversity and boundary regions in Vincetoxicum chloroplast genomes revealed relatively conserved genomic features alongside highly variable regions.
conclusionsOur findings provide essential technical support for molecular breeding of V. pycnostelma and rapid identification of its medicinal materials, which may facilitate sustainable industrial development.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.