Evidence map›Paper›PMID 41419899›Full record

ArticleBMC palliative care2025

A mixed methods process evaluation of a collaborative outpatient palliative care clinic for patients with end-stage liver disease.

Grace Warmels, Aria Wills, Adrianna Bruni, Leila Cohen, Erin Kelly, James Downar, Arpan A Patel, Greg Dargavel, Shreya Rauthu, Sarina R Isenberg

Abstract read
In one paragraph

Article in BMC palliative care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Grace WarmelsBruyere Health Research Institute, Ottawa, Canada. gwarmels@toh.ca.
Aria WillsBruyere Health Research Institute, Ottawa, Canada.
Adrianna BruniOttawa Hospital Research Institute, Ottawa, Canada.
Leila CohenOttawa Hospital Research Institute, Ottawa, Canada.
Erin KellyOttawa Hospital Research Institute, Ottawa, Canada.
James DownarBruyere Health Research Institute, Ottawa, Canada.
Arpan A PatelVA Greater Los Angeles Healthcare System, California, USA.
Greg Dargavel, Ottawa, Ontario, Canada.
Shreya Rauthu, Ottawa, Ontario, Canada.
Sarina R IsenbergBruyere Health Research Institute, Ottawa, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with end-stage liver disease (ESLD) have significant symptoms and limited prognosis, yet receive less palliative care (PC) than patients with cancer. The optimal outpatient PC model for patients with ESLD remains unclear.

objectiveWe used process evaluation methodology to evaluate a novel PC clinic for patients with ESLD in Ottawa, Canada.

designWe conducted a convergent parallel mixed methods study, informed by a logic model and process evaluation framework co-designed with a caregiver partner. Qualitative inputs included semi-structured interviews conducted with patients, family caregivers, as well as PC and hepatology clinicians, and analyzed using applied thematic analysis. Quantitative inputs included data collected through a retrospective chart review, analyzing healthcare utilization up to six months before and after consultation.

participantsInterviews conducted with eight healthcare providers (HCPs) and 13 patients and caregivers. Chart review performed for 46 patients seen in the clinic between October 2020 and June 2023.

interventionAn outpatient PC hepatology collaboration clinic, led by specialist PC physicians. APPROACH: Qualitative and quantitative data were analyzed independently and then triangulated for overall interpretation. KEY

resultsThe evaluation demonstrated the achievement of the outcomes in the logic model and process evaluation domains. Interviews highlighted high satisfaction among HCPs, patients, and caregivers, and effective collaboration between the PC and hepatology teams. Perceived barriers include the burden of in-person appointments. Quantitative results indicated decreased acute healthcare utilization in the six months following PC consultation compared to the six months prior. Over 50% of the deceased patients died outside of the hospital.

conclusionThe early outpatient PC clinic provides high-quality, collaborative care for patients with ESLD; study findings suggest an association with reduced acute healthcare utilization and increased likelihood of death occurring outside the hospital. This model represents a promising approach for PC in ESLD and other non-malignant illnesses.

Indexed as

End Stage Liver DiseasePalliative CareAgedAged, 80 and overAmbulatory CareAmbulatory Care FacilitiesCanadaCooperative BehaviorFemaleHumansInterviews as TopicMaleMiddle AgedOntarioQualitative ResearchRetrospective StudiesCirrhosisEnd-stage liver diseaseMixed methodsPalliative careProcess evaluation

Identifiers

PMID41419899
PMCPMC12831412

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.