Article in EMBO molecular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
14 authors.
Márcio Augusto Campos-RibeiroInstitut Pasteur, CNRS UMR 3691, Mitochondrial Biology Unit, Université Paris Cité, Paris, 25-28 Rue du Docteur Roux, 75015, France.ORCID 0000-0002-8431-4968
Erminia DonnarummaInstitut Pasteur, CNRS UMR 3691, Mitochondrial Biology Unit, Université Paris Cité, Paris, 25-28 Rue du Docteur Roux, 75015, France.ORCID 0000-0003-2184-5144
Hendrik NolteMax-Planck-Institute for Biology of Ageing, Department of Mitochondrial Proteostasis, Joseph-Stelzmann-Str. 9b, Cologne, 50931, Germany.
Paul CobineDepartment of Biological Sciences, Auburn University, Auburn, AL, USA.ORCID 0000-0001-6012-0985
Elodie VimontInstitut Pasteur, CNRS UMR 3691, Mitochondrial Biology Unit, Université Paris Cité, Paris, 25-28 Rue du Docteur Roux, 75015, France.
Dusanka MilenkovicMax-Planck-Institute for Biology of Ageing, Department of Mitochondrial Proteostasis, Joseph-Stelzmann-Str. 9b, Cologne, 50931, Germany.ORCID 0000-0003-0151-8760
Juan Diego Hernandez-CamachoInstitut Pasteur, CNRS UMR 3691, Mitochondrial Biology Unit, Université Paris Cité, Paris, 25-28 Rue du Docteur Roux, 75015, France.ORCID 0000-0001-9726-6726
Francina Langa-VivesInstitut Pasteur, Mouse Genetics Engineering Center, Université Paris Cité, Paris, 25-28 Rue du Docteur Roux, 75015, France.ORCID 0000-0002-0801-5464
Etienne KornobisInstitut Pasteur, Biomics core facility, Bioinformatics and Biostatistics Hub, Université Paris Cité, Paris, 25-28 Rue du Docteur Roux, 75015, France.ORCID 0000-0001-7712-8270
Esthel PénardInstitut Pasteur, Ultrastructural Bioimaging Core Facility, Université Paris Cité, Paris, 25-28 Rue du Docteur Roux, 75015, France.ORCID 0000-0002-4442-7503
Sonny YdeInstitut Pasteur, CNRS UMR 3691, Mitochondrial Biology Unit, Université Paris Cité, Paris, 25-28 Rue du Docteur Roux, 75015, France.
Thomas LangerMax-Planck-Institute for Biology of Ageing, Department of Mitochondrial Proteostasis, Joseph-Stelzmann-Str. 9b, Cologne, 50931, Germany.ORCID 0000-0003-1250-1462
Véronique Paquis-FlucklingerUniversité Côte d'Azur (UniCA), Inserm U1081, CNRS UMR7284, Institute for Research and Aging (IRCAN), Mitochondria, Disease and Aging Team, Nice, France.
Timothy WaiInstitut Pasteur, CNRS UMR 3691, Mitochondrial Biology Unit, Université Paris Cité, Paris, 25-28 Rue du Docteur Roux, 75015, France. timothy.wai@pasteur.fr.ORCID 0000-0002-6770-6222
Funding
Agence Nationale de la Recherche (ANR) ANR-10-INSB-04-01Agence Nationale de la Recherche (ANR) ANR-10-LABX-62-IBEIDAgence Nationale de la Recherche (ANR) ANR-21-CE14 0052-02Agence Nationale de la Recherche (ANR) ANR-23-CE13-0043-01Institut Pasteur (Pasteur Institute) INNOV 164-2022
6 · The paper itself
Abstract
Mutations in CHCHD10, a mitochondrial intermembrane space (IMS) protein implicated in proteostasis and cristae maintenance, cause mitochondrial disease. Knock-in mice modeling the human CHCHD10
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.
Mutant CHCHD10 disrupts cytochrome c oxidation and activates mitochondrial retrograde signaling. · full record | Socratic