Evidence map›Paper›PMID 41420195›Full record

ArticleVirology journal2025

Peripheral and intrahepatic B-cell subsets contribute to HBeAg seroconversion in patients with chronic hepatitis B.

Jing Zuo, Xue-Qi Yang, Fang-Ming Zhou, Zheng-Jie Qu, Yu-Xin Tian, Jie-Ru Yang, Yu-Chen Fan

Abstract read
In one paragraph

Article in Virology journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jing ZuoDepartment of Hepatology, Qilu Hospital of Shandong University, Jinan, 250012, China.
Xue-Qi YangDepartment of Hepatology, Qilu Hospital of Shandong University, Jinan, 250012, China.
Fang-Ming ZhouSchool of Public Health and Health Management, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, 250014, China.
Zheng-Jie QuSchool of Public Health and Health Management, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, 250014, China.
Yu-Xin TianDepartment of Hepatology, Qilu Hospital of Shandong University, Jinan, 250012, China.
Jie-Ru YangDepartment of Hepatology, Qilu Hospital of Shandong University, Jinan, 250012, China.
Yu-Chen FanDepartment of Hepatology, Qilu Hospital of Shandong University, Jinan, 250012, China. pyfanyuchen@126.com.

Funding

Clinical Research Center of Shandong University 2021SDUCRCB006National Natural Science Foundation of China 82270631Young Taishan Scholars tsqn202103169
6 · The paper itself

Abstract

The immunopathogenesis of chronic hepatitis B (CHB) with unclear immune phases hinders functional cure. For highly infectious HBeAg-positive (HBeAg

Indexed as

B-Lymphocyte SubsetsHepatitis B, ChronicHepatitis B e AntigensLiverSeroconversionAdultFemaleHepatitis B virusHumansMaleMiddle AgedSingle-Cell AnalysisHepatitis B e AntigensB cellsChronic hepatitis B (CHB)HBeAg-negative (HBeAg⁻) chronic HBV infectionHBeAg seroconversionHBV clearance

Identifiers

PMID41420195
PMCPMC12836816

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.