ArticleTranslational psychiatry2025
Peripheral cyclical expression of GABA-A receptor subunit genes and menstrual cycle affective change: a dimensional, transdiagnostic study.
Jordan C Barone, Raffaele Romano, Anisha Nagpal, Antonio Salerno, Anna Patterson, Elizabeth S Wenzel, Gabriela Guzman, Viraja Alluri, Pauline Maki, Graziano Pinna and 1 more
Abstract read
In one paragraphArticle in Translational psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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2 · The registryThe trial behind it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
11 authors.
Gabriela GuzmanDepartment of Psychiatry, University of Illinois Chicago, Chicago, IL, US.
Viraja AlluriDepartment of Psychiatry, University of Illinois Chicago, Chicago, IL, US.
Pauline MakiDepartment of Psychiatry, University of Illinois Chicago, Chicago, IL, US.
Funding
Training in the Neuroscience of Mental HealthT32MH067631 · NIMH · UNIVERSITY OF ILLINOIS AT CHICAGO · PI RASENICK, MARK M. · 2004 to 2024
$4.8MCyclical Neuroactive Steroid Changes, Arousal, and Proximal Suicide Risk: An Experimental ApproachRF1MH120843 · NIMH · UNIVERSITY OF ILLINOIS AT CHICAGO · PI EISENLOHR-MOUL, TORY ANNE · 2019 to 2019
$3.1M1/2 Allopregnanolone and Dynamic GABA-A Receptor Plasticity in Selective Serotonin Reuptake Inhibitor Responsive Premenstrual Dysphoric DisorderR01MH134904 · NIMH · JOHNS HOPKINS UNIVERSITY · PI Liisa Victoria Hantsoo, GRAZIANO PINNA · 2024 to 2026
$1.4MSleep as a Mechanism of Premenstrual Exacerbation of Depression and SuicidalityF30MH138058 · NIMH · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Anisha Nagpal · 2024 to 2026
$164kNIMH NIH HHS F30 MH138058NIMH NIH HHS R01 MH134904NIMH NIH HHS RF1 MH120843NIMH NIH HHS T32 MH067631U.S. Department of Defense (United States Department of Defense) HT9425-25-1-0261U.S. Department of Health & Human Services | National Institutes of Health (NIH) R01MH134904U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (NIMH) RF1MH120843U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (NIMH) T32MH067631
6 · The paper itselfAbstract
Menstrual cycle affective change (MCAC), including conditions like Premenstrual Dysphoric Disorder (PMDD), is triggered by ovarian hormone fluctuations, but its neurobiological mechanisms remain poorly understood. A leading hypothesis implicates abnormal GABA-A receptor (GABA
Indexed as
Menstrual CyclePremenstrual Dysphoric DisorderReceptors, GABA-AAdultAnxietyFemaleGene ExpressionHumansMiddle AgedRNA, MessengerYoung AdultGABRA2 protein, humanGABRA5 protein, humanGABRG2 protein, humanReceptors, GABA-ARNA, Messenger
Identifiers
PMID41422264
PMCPMC12722714
What Socratic holds
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LicenceCC BY-NC-ND
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