Evidence map›Paper›PMID 41422268›Full record

ArticleScientific reports2025

Comparative molecular profiling of Helicobacter pylori infection and antibiotic genotypic resistance in paired gastric mucosa, gastric juice, and stool samples.

Jianping Cheng, Chanjuan Fan, Xiaolin Zhao, Zhen Li, Dongling Xie, Yong Cai, Kun Huang, Mengyuan Yang, Hui Wang

Abstract readComparative Study
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Simultaneous point-of-care detection and virulence typing of Helicobacter pylori using multiplex recombinase polymerase amplification combined with lateral flow strip.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  2. Article
  3. Advances in the Management of RefractoryGastro hep advances · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jianping ChengDepartment of Gastroenterology, Civil Aviation General Hospital, Beijing, 100123, China. cjpczy2004@163.com.
Chanjuan FanDepartment of Gastroenterology, Civil Aviation General Hospital, Beijing, 100123, China.
Xiaolin ZhaoDepartment of Gastroenterology, Civil Aviation General Hospital, Beijing, 100123, China.
Zhen LiDepartment of Gastroenterology, Civil Aviation General Hospital, Beijing, 100123, China.
Dongling XieDepartment of Gastroenterology, Civil Aviation General Hospital, Beijing, 100123, China.
Yong CaiDepartment of Gastroenterology, Civil Aviation General Hospital, Beijing, 100123, China.
Kun HuangDepartment of Gastroenterology, Civil Aviation General Hospital, Beijing, 100123, China.
Mengyuan YangDepartment of Gastroenterology, Civil Aviation General Hospital, Beijing, 100123, China.
Hui WangDepartment of Gastroenterology, Civil Aviation General Hospital, Beijing, 100123, China.

Funding

the major project of Civil Aviation General Hospital 202302
6 · The paper itself

Abstract

Increasing antibiotic resistance in Helicobacter pylori (H. pylori) is undermining empirical eradication therapies. Non-invasive methods for resistance profiling are urgently needed to guide precision treatment. This study aimed to compare the performance of paired gastric juice and stool samples against gastric mucosa for the detection of H. pylori infection and genotypic resistance to clarithromycin and levofloxacin. In this prospective study, patients with H. pylori infection confirmed through positive

Indexed as

Drug Resistance, BacterialFecesGastric JuiceGastric MucosaHelicobacter InfectionsHelicobacter pyloriAdultAgedAnti-Bacterial AgentsClarithromycinFemaleGenotypeHumansLevofloxacinMaleMicrobial Sensitivity TestsAnti-Bacterial AgentsClarithromycinLevofloxacinAntibiotic resistanceGastric juiceHelicobacter pyloriMolecular diagnosticsPersonalized medicine

Identifiers

PMID41422268
PMCPMC12830849

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.