Evidence map›Paper›PMID 41422499›Full record

ArticleCancer medicine2025

Impact of Postdiagnosis Health Behaviors and Behavior Changes on Prognosis in Colorectal Cancer Patients: Evidence From Real-World Data.

Donghyun Won, Ji Yoon Baek, Ji Won Park, Jeeyoo Lee, Sooyoung Cho, Aesun Shin

Abstract read
In one paragraph

Article in Cancer medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Donghyun WonDepartment of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea.
Ji Yoon BaekDepartment of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea.
Ji Won ParkDepartment of Surgery, Seoul National University Hospital, Seoul, Korea.
Jeeyoo LeeDepartment of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea.
Sooyoung ChoGenomic Medicine Institute, Medical Research Center, Seoul National University, Seoul, Korea.
Aesun ShinDepartment of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-6426-1969

Funding

National Research Foundation of Korea 2022R1A2C1004608
6 · The paper itself

Abstract

backgroundColorectal cancer (CRC) is a prevalent cancer worldwide, but encouraging healthier lifestyle choices among survivors may improve their prognosis. We aimed to evaluate health habits adopted after diagnosis and their impact on prognosis.

methodsFor this population-based retrospective cohort study, we used data from the Cancer Public Library Database (CPLD), which consists of four major population-based public sources in Korea with cancer patients diagnosed between 2012 and 2019. Information on anthropometric measures, physical activity, alcohol consumption, and smoking status before and after cancer diagnosis was used. Hazard ratios (HRs) for all-cause deaths with 95% confidence intervals (CIs) were estimated via the Cox proportional hazards model.

resultsAmong the 7553 CRC patients, postdiagnosis physical activity was significantly related to decreased risk of death among those who were diagnosed with stage I or III CRC (p for trend < 0.05). The analysis of 4588 patients revealed that increased physical activity (stage I: adjusted HR [aHR] = 0.60, 95% CI = 0.29-1.22; stage II: aHR = 0.86, 95% CI = 0.49-1.52; stage III: aHR = 0.60, 95% CI = 0.36-0.99) or smoking cessation (stage I: aHR = 0.81, 95% CI = 0.28-2.35; stage II: aHR = 0.36, 95% CI = 0.16-0.81; stage III: aHR = 0.89, 95% CI = 0.42-1.87), were associated with poor prognosis compared to those who consistently remained physically inactive or continued to smoke.

conclusionThe present study provides compelling evidence on the benefits of increased physical activity and smoking cessation after CRC diagnosis for improved survival.

Indexed as

Colorectal NeoplasmsHealth BehaviorAdultAgedAlcohol DrinkingExerciseFemaleHumansMaleMiddle AgedNeoplasm StagingPrognosisRepublic of KoreaRetrospective StudiesSmokingcancer epidemiologycolorectal cancerlong‐term survivalpostdiagnosis behaviors

Identifiers

PMID41422499
PMCPMC12718552

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.