Evidence map›Paper›PMID 41423276›Full record

ArticleThoracic cancer2025

Diagnostic Value of Photon-Counting CT in Pericardial Metastases: A Single-Center Retrospective Study.

Hui Wang, Yuqin Jin, Yuangang Qi, Feng Liu, Haoran Chen, Yong Huang, Jian Zhu, Yuhui Liu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Thoracic cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hui WangDepartment of Special Examination, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China.
Yuqin JinDepartment of Radiology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China.
Yuangang QiDepartment of Radiology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China.
Feng LiuSchool of Information Engineering, Shandong Youth University of Political Science, Jinan, China.
Haoran ChenDepartment of Radiology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China.
Yong HuangDepartment of Radiology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China.
Jian ZhuDepartment of Radiological Physics and Technology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China.
Yuhui LiuDepartment of Radiology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China.ORCID https://orcid.org/0000-0003-0867-3632

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pericardial metastases are common in advanced cancers but often remain undetected due to subtle symptoms. Photon-counting CT (PCT) offers improved spatial resolution and contrast-to-noise ratio (CNR) compared with conventional CT (CCT), potentially enhancing diagnostic performance. In this retrospective single-center study, patients diagnosed with pericardial metastases by transthoracic echocardiography (TTE) between April and September 2025, who underwent both unenhanced and contrast-enhanced chest CT were included. After Propensity Score Matching (PSM), two groups were established: the PCT group (n = 11; reconstructions at 0.4 and 1 mm) and the CCT group (n = 22). Diagnostic sensitivity, image quality, and radiation dose were assessed, with TTE as the reference standard. PCT-0.4 mm demonstrated the highest overall sensitivity (91.5%) and small-lesion sensitivity (88.9%), followed by PCT-1 mm (87.2% and 83.3%) and CCT-1 mm (86.1% and 78.6%). Although not statistically significant, PCT showed consistently better lesion detection. The PCT-0.4 mm group showed higher standardized CNR versus CCT-1 mm (Tukey-Kramer p = 0.021) but not versus PCT-1 mm (p = 0.641); overall one-way ANOVA p = 0.020, whereas SNR did not differ among groups (ANOVA p = 0.18). Radiation exposure was significantly lower with PCT than CCT (ED: 11.7 ± 3.9 vs. 20.6 ± 6.6 mSv; p < 0.001). Compared with the 1-mm CCT reconstruction, the 0.4-mm PCT showed a trend toward improved detection of both overall and small pericardial metastases, enhanced image quality, and reduced radiation dose, highlighting its potential clinical value in managing pericardial metastases.

Indexed as

Heart NeoplasmsPericardiumPhotonsTomography, X-Ray ComputedAgedFemaleHumansMaleMiddle AgedRetrospective Studiesdiagnostic sensitivitypericardial metastasesphoton‐counting CTradiation dosetransthoracic echocardiography

Identifiers

PMID41423276
PMCPMC12875143

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.