Evidence map›Paper›PMID 41423541›Full record

ArticleHormones (Athens, Greece)2026

The impact of obesity-related anthropometric indices on diabetic foot ulcer and mortality: analysis of a nationally representative sample.

ZhaoLiang Zhang, LiMing Zhou, YunFei Xu, LieHui Yao, Tao Ma, XiaYun Pan

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Article in Hormones (Athens, Greece), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

ZhaoLiang ZhangThe Affiliated YiXing Hospital of Jiangsu University, YiXing, 214200, JiangSu, China.
LiMing ZhouThe Affiliated YiXing Hospital of Jiangsu University, YiXing, 214200, JiangSu, China.
YunFei XuThe Affiliated YiXing Hospital of Jiangsu University, YiXing, 214200, JiangSu, China.
LieHui YaoThe Affiliated YiXing Hospital of Jiangsu University, YiXing, 214200, JiangSu, China.
Tao MaThe Affiliated YiXing Hospital of Jiangsu University, YiXing, 214200, JiangSu, China.
XiaYun PanThe Affiliated YiXing Hospital of Jiangsu University, YiXing, 214200, JiangSu, China. staff6413@yxph.com.

Funding

Yixing People's Hospital YRY2025B002
6 · The paper itself

Abstract

AIMS AND

backgroundDiabetic foot ulcer (DFU) is a serious diabetes complication and a leading cause of non-traumatic lower extremity amputation. Obesity-related anthropometric indices may serve as early predictors of DFU. This study examined associations between the following four indices: body mass index (BMI), weight-adjusted waist index (WWI), body roundness index (BRI), and relative fat mass (RFM), and DFU risk.

methodsData were drawn from the 1999-2004 U.S. National Health and Nutrition Examination Survey (NHANES). Weighted multivariable regression, restricted cubic spline models, and ROC curve analyses were used to assess associations. Subgroup and sensitivity analyses were also conducted.

resultsAmong 1,487 people with diabetes, 100 had DFU and 733 had pre-DFU symptoms. DFU patients showed higher HbA1c and UACR levels. After adjusting for confounders, all four indices were positively associated with DFU: BMI (OR = 1.07), WWI (OR = 1.95), BRI (OR = 1.47), and RFM (OR = 1.13). However, no significant associations were found between the indices and pre-DFU. Non-linear analysis suggested a potential curved relationship between WWI and DFU. Additionally, WWI (HR = 1.34) and BRI (HR = 1.18) were linked to increased all-cause mortality. Subgroup and sensitivity analyses confirmed robustness of the results.

conclusionsBMI, WWI, BRI, and RFM were all independently associated with DFU, while WWI and BRI were also predictors of all-cause mortality in people with diabetes. These anthropometric markers may aid in early identification and management of high-risk individuals.

Indexed as

Body Mass IndexDiabetic FootObesityAgedFemaleHumansMaleMiddle AgedNutrition SurveysRisk FactorsUnited StatesDiabetic foot ulcerMortalityNHANESObesity indicatorsPredictive markers

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.