Evidence map›Paper›PMID 41423689›Full record

ArticleJournal of diabetes2025

Course of Carpal Tunnel Syndrome Management in Patients With Diabetes.

Sophia Xiao, Ignacio Garcia Fleury, Natalie Glass, Joseph Buckwalter

Abstract read
In one paragraph

Article in Journal of diabetes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sophia XiaoCarver College of Medicine, University of Iowa, Iowa City, Iowa, USA.ORCID https://orcid.org/0000-0002-0517-2229
Ignacio Garcia FleuryDepartment of Orthopedics and Rehabilitation, University of Iowa, Iowa City, Iowa, USA.
Natalie GlassDepartment of Orthopedics and Rehabilitation, University of Iowa, Iowa City, Iowa, USA.
Joseph BuckwalterDepartment of Orthopedics and Rehabilitation, University of Iowa, Iowa City, Iowa, USA.

Funding

Iowa Medical Student Summer Research Program in trans-NIDDK ResearchT35DK135446 · NIDDK · UNIVERSITY OF IOWA · PI ROBERT D ROGHAIR · 2023 to 2026
$418k
NHLBI NIH HHS T35DK135446NIDDK NIH HHS T35 DK135446NIH HHSUniversity of Iowa Department of Orthopedics and Rehabilitation
6 · The paper itself

Abstract

backgroundCarpal Tunnel Syndrome (CTS) is the most prevalent compressive neuropathy, often worsened by microvasculopathy in diabetic neuropathy. Diabetes mellitus (DM) patients experience increased CTS risk but are frequently underdiagnosed. This study investigates the progression to CTS diagnosis and CT release (CTR) in DM patients, aimed at better early detection and CTS prevention.

methodsData including age and HbA1c from 304 patients with CTS, DM, and CTR (2012-2022) was collected from a tertiary care center. CTS-CTR time was compared between patients diagnosed with DM pre- or post-CTS using Wilcoxon rank-sum tests. Analyses were conducted using SAS v9.4. Relationships between age or HbA1c and CTS-CTR or DM-CTS timelines were described by Spearman correlation coefficients.

results51% (n = 154) of patients received DM diagnosis post-CTS identification. Time between diagnoses was similar in patients diagnosed with DM before vs. after CTS (24.6 (8.0-41.8), 24.3 (9.9-46.2) months, p = 0.604). From CTS to first CTR, the median time difference was 2.5 months (1.0-8.1) with no significant impact from DM diagnosis timing (before: 2.57, after: 2.20 months, p = 0.188). CTS-CTR time correlated with age (

conclusionsOver half of CTR patients were diagnosed with DM before CTS, underscoring the urgency for assessing new DM patients for CTS symptoms. Future clinical programs should target early identification of CTS signs and optimal timing for surgical interventions to enhance patient well-being.

Indexed as

Carpal Tunnel SyndromeDiabetes MellitusDiabetic NeuropathiesAdultAgedDisease ManagementDisease ProgressionFemaleGlycated HemoglobinHumansMaleMiddle AgedGlycated Hemoglobinhemoglobin A1c protein, humancarpal tunnel syndromediabetes complicationsdiabetes mellitusdiabetic neuropathiesmedian neuropathy

Identifiers

PMID41423689
PMCPMC12719237

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.