Evidence map›Paper›PMID 41424864›Full record

ArticleTheranostics2026

Chronic intermittent hypoxia increases Parkinson's disease susceptibility via PPARα-mediated lipid droplet-mitochondrial dysfunction.

Ming-Rui Zhai, Jie Pan, Zhen-Huan Wu, Yu-Ying He, Kai-Run Zhang, Long Ren, Yu-Rong Wang, Yi-Bing Li, Jun Gao, Lei Xiao and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Theranostics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ming-Rui ZhaiDepartment of Orthodontics, Shanghai Stomatological Hospital & School of Stomatology, Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, and the Institutes of Brain Science, Fudan University, China.
Jie PanDepartment of Orthodontics, Shanghai Stomatological Hospital & School of Stomatology, Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, and the Institutes of Brain Science, Fudan University, China.
Zhen-Huan WuDepartment of Orthodontics, Shanghai Stomatological Hospital & School of Stomatology, Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, and the Institutes of Brain Science, Fudan University, China.
Yu-Ying HeDepartment of Orthodontics, Shanghai Stomatological Hospital & School of Stomatology, Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, and the Institutes of Brain Science, Fudan University, China.
Kai-Run ZhangDepartment of Orthodontics, Shanghai Stomatological Hospital & School of Stomatology, Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, and the Institutes of Brain Science, Fudan University, China.
Long RenDepartment of Orthodontics, Shanghai Stomatological Hospital & School of Stomatology, Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, and the Institutes of Brain Science, Fudan University, China.
Yu-Rong WangDepartment of Orthodontics, Shanghai Stomatological Hospital & School of Stomatology, Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, and the Institutes of Brain Science, Fudan University, China.
Yi-Bing LiDepartment of Orthodontics, Shanghai Stomatological Hospital & School of Stomatology, Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, and the Institutes of Brain Science, Fudan University, China.
Jun GaoDepartment of Orthodontics, Shanghai Stomatological Hospital & School of Stomatology, Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, and the Institutes of Brain Science, Fudan University, China.
Lei XiaoDepartment of Orthodontics, Shanghai Stomatological Hospital & School of Stomatology, Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, and the Institutes of Brain Science, Fudan University, China.
Yue-Hua LiuDepartment of Orthodontics, Shanghai Stomatological Hospital & School of Stomatology, Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, and the Institutes of Brain Science, Fudan University, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HypoxiaLipid DropletsMitochondriaParkinson DiseasePPAR alphaAnimalsDisease Models, AnimalDisease SusceptibilityDopaminergic NeuronsHumansLipid MetabolismMaleMiceMice, Inbred C57BLSleep Apnea, ObstructivePPAR alphaPpara protein, mousechronic intermittent hypoxialipid dropletmitochondriaobstructive sleep apneaParkinson's diseasePPARα

Identifiers

PMID41424864
PMCPMC12712921

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.