ArticleInternational journal of women's health2025
Association of Dietary Inflammation Index with Infertility Risk in US Women: A Cross-Sectional Analysis from NHANES (2013-2020).
Article in International journal of women's health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: This study investigates the relationship between the Dietary Inflammation Index (DII) and the risk of infertility among women of childbearing age in the United States. Methods: This cross-sectional study analyzed data from 3184 women aged 20 to 45 years, utilizing information from the National Health and Nutrition Examination Survey (NHANES, 2013-2020). Dietary intake was assessed using 24-hour recall interviews to calculate the DII score, which is based on 28 dietary components. The DII score is used to assess the inflammatory potential of diet, with higher scores indicating a greater likelihood of inducing inflammation. Multivariate logistic regression and restricted cubic splines (RCS) were employed to evaluate the association between DII and infertility risk, adjusting for potential confounders such as age, BMI, and lifestyle factors. LASSO regression was used to identify key predictors, and a nomogram for predicting infertility risk was developed. Results: Among the participants, 12.41% were classified as infertile. Women with infertility had significantly higher DII scores compared to those without infertility (2.27 [1.09, 3.14] vs 1.99 [0.92, 2.97]; p =0.016). The analysis revealed a positive association between higher DII scores and increased infertility risk, even after adjusting for confounding variables. RCS analysis indicated no significant nonlinear relationship between DII and infertility (p for non-linearity = 0.118). Furthermore, DII was identified as a more effective predictor of infertility risk than the Healthy Eating Index (HEI). The nomogram prediction model, developed from the predictive factors identified via LASSO regression, exhibited robust predictive performance, achieving an AUC of 85.1% (95% CI: 74.7%-95.5%). Conclusion: A pro-inflammatory diet, indicated by a high Dietary Inflammatory Index (DII) score, is associated with an elevated risk of infertility in American women, thereby supporting dietary interventions to reduce inflammation for improved fertility outcomes and highlighting the relevance of dietary counseling in fertility care.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.