ArticleFrontiers in immunology2025
Clinical review of adult Henoch-Schönlein purpura and analysis of predictors related to gastrointestinal involvement.
Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Adult IgA Vasculitis: Clinical Characteristics, Management, and Outcomes in 37 Patients.International journal of dermatology · 2026Article
- Adult-onset IgA Vasculitis Initially Attributed to a Cutaneous Drug Reaction and Diverticulitis.Journal of community hospital internal medicine perspectives · 2026Article
- Association of the inflammation indicators with multiple system involved of immunoglobulin A vasculitis in children.Frontiers in pediatrics · 2026Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Henoch-Schönlein purpura (HSP) is a small-vessel vasculitis characterized by non-thrombocytopenic purpura, often involving the gastrointestinal tract, joints, kidneys, and other organs. While most studies on HSP focus on children, severe manifestations and poor outcomes are more frequently observed in adults. Objective: This retrospective study aimed to evaluate predictors associated with gastrointestinal (GI) involvement in adult patients. Methods: We included 206 adult patients with HSP, categorized into subgroups based on the presence of gastrointestinal involvement. Results: Among the 206 patients, 22.82% had gastrointestinal (GI+) involvement, while 77.18% had non-gastrointestinal (GI-) involvement. The GI+ group exhibited significantly higher rates of skin lesions extending to both lower limbs, atypical rashes such as blisters and necrosis, and joint involvement compared to the GI- group ( Conclusions: Adult HSP patients with gastrointestinal involvement are more likely to present with extensive skin lesions, atypical rashes, and joint involvement; may be at risk of misdiagnosis; and have elevated D-dimer levels.
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Registered trials
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