Evidence map›Paper›PMID 41425624›Full record

ReviewFrontiers in nutrition2025

Beyond seasoning nutrients bioactive ingredients and healthcare effects of Allium vegetables.

Hafiz Ghulam Muhu Din Ahmed, Jiazhen Yang, Tong Zhu, Rashid Iqbal, Qing Sheng, Ruijie Dong, Wenhuai Tian, Lei Xiao, Yawen Zeng, Yumei Ding

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hafiz Ghulam Muhu Din Ahmed *Department of Plant Breeding and Genetics, Faculty of Agriculture and Environment, The Islamia University of Bahawalpur, Bahawalpur, Pakistan.
Jiazhen Yang *Biotechnology and Germplasm Resources Institute, Yunnan Academy of Agricultural Sciences, Kunming, China.
Tong ZhuCollege of Food Science and Technology, Yunnan Agricultural University, Kunming, China.
Rashid IqbalDepartment of Agronomy, Faculty of Agriculture and Environment, The Islamia University of Bahawalpur, Bahawalpur, Pakistan.
Qing ShengCollege of Food Science and Technology, Yunnan Agricultural University, Kunming, China.
Ruijie DongCollege of Food Science and Technology, Yunnan Agricultural University, Kunming, China.
Wenhuai TianCollege of Food Science and Technology, Yunnan Agricultural University, Kunming, China.
Lei XiaoCollege of Food Science and Technology, Yunnan Agricultural University, Kunming, China.
Yawen ZengBiotechnology and Germplasm Resources Institute, Yunnan Academy of Agricultural Sciences, Kunming, China.
Yumei DingCollege of Food Science and Technology, Yunnan Agricultural University, Kunming, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review highlights the nutritional and therapeutic significance of Allium vegetables-including garlic, onion, leek, and chive-emphasizing their principal bioactive compounds such as organosulfur compounds, flavonoids, and essential micronutrients. These phytochemicals exhibit potent antioxidant, anti-inflammatory, and anticancer activities that contribute to the prevention and management of chronic diseases including cancer, diabetes, and cardiovascular disorders. Mechanistic studies indicate that Allium-derived compounds modulate oxidative stress and inflammatory pathways through NF-κB and Nrf2 signaling, thereby enhancing metabolic and immune resilience. Despite these well-established benefits, challenges such as low bioavailability, inter-species variability, and limited clinical validation restrict translational potential. Recent advances in nanoencapsulation, emulsion-based delivery, and inclusion complexes offer promising strategies to improve compound stability and absorption. Future research should integrate clinical validation, comparative genomics, and functional food formulation to maximize health outcomes. This review underscores Allium vegetables as promising functional foods for preventive healthcare and supports their integration into daily diets to promote sustainable wellbeing.

Indexed as

Allium vegetablesantioxidantsbioactive compoundsbioavailabilityflavonoidsfunctional foodsorganosulfur compoundspreventive healthcare

Identifiers

PMID41425624
PMCPMC12715821

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.