Evidence map›Paper›PMID 41425934›Full record

ArticleFrontiers in microbiology2025

ClpB affects biofilm formation in methicillin-resistant

Miao Yang, Shuang Wang, Qianwei Qu, Hai Yang, Xin Liu, Wei Peng, Yonghui Zhou

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Miao Yang *School of Basic Medicine, Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou, China.
Shuang Wang *School of Basic Medicine, Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou, China.
Qianwei QuCollege of Veterinary Medicine, Northeast Agricultural University, Harbin, Heilongjiang, China.
Hai YangDepartment of Pathology, The First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou, China.
Xin LiuSchool of Basic Medicine, Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou, China.
Wei PengSchool of Basic Medicine, Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou, China.
Yonghui ZhouSchool of Basic Medicine, Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: This study aims to explore the effects of the molecular chaperone ClpB on the biofilm formation and pathogenicity of methicillin-resistant Methods: The biological membrane formation was evaluated by constructing a Results: The results showed that compared with the wild strain (WT), the biomass of Δ Conclusion: ClpB promotes the formation of MRSA biofilms by regulating extracellular matrix synthesis and host inflammatory responses and is a potential target for anti-biofilm therapy.

Indexed as

biofilmClpBextracellular matrixMRSAskin infection

Identifiers

PMID41425934
PMCPMC12711867

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.