Evidence map›Paper›PMID 41426372›Full record

ArticlePediatric investigation2025

Infectious mononucleosis complicated with Kawasaki disease: Two case reports and literature review.

Mengjia Liu, Lingyun Guo, Qinjing Li, Dilara Dilmurat, Gang Liu, Zhengde Xie

Abstract read
In one paragraph

Article in Pediatric investigation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Recent progress in understanding ferroptosis mechanisms in infectious diseases.Frontiers in cellular and infection microbiology · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mengjia LiuInstitute of Pathogen Biology Chinese Academy of Medical Sciences & Peking Union Medical College Beijing China.
Lingyun GuoDepartment of Infectious Diseases National Center for Children's Health National Center for Children's Infectious and Allergic Diseases Surveillance Beijing Research Center for Respiratory Infectious Diseases Beijing Key Laboratory of Core Technologies for the Prevention and Treatment of Emerging Infectious Diseases in Children Key Laboratory of Major Diseases in Children Ministry of Education Beijing Children's Hospital Capital Medical University Beijing China.
Qinjing LiDepartment of Infectious Diseases National Center for Children's Health National Center for Children's Infectious and Allergic Diseases Surveillance Beijing Research Center for Respiratory Infectious Diseases Beijing Key Laboratory of Core Technologies for the Prevention and Treatment of Emerging Infectious Diseases in Children Key Laboratory of Major Diseases in Children Ministry of Education Beijing Children's Hospital Capital Medical University Beijing China.
Dilara DilmuratBeijing Research Center for Respiratory Infectious Diseases Beijing Key Laboratory of Core Technologies for the Prevention and Treatment of Emerging Infectious Diseases in Children Key Laboratory of Major Diseases in Children Ministry of Education National Clinical Research Center for Respiratory Diseases Laboratory of Infection and Virology Beijing Pediatric Research Institute Beijing Children' s Hospital Capital Medical University National Center for Children's Health Beijing China.
Gang LiuDepartment of Infectious Diseases National Center for Children's Health National Center for Children's Infectious and Allergic Diseases Surveillance Beijing Research Center for Respiratory Infectious Diseases Beijing Key Laboratory of Core Technologies for the Prevention and Treatment of Emerging Infectious Diseases in Children Key Laboratory of Major Diseases in Children Ministry of Education Beijing Children's Hospital Capital Medical University Beijing China.ORCID https://orcid.org/0000-0001-8551-741X
Zhengde XieBeijing Research Center for Respiratory Infectious Diseases Beijing Key Laboratory of Core Technologies for the Prevention and Treatment of Emerging Infectious Diseases in Children Key Laboratory of Major Diseases in Children Ministry of Education National Clinical Research Center for Respiratory Diseases Laboratory of Infection and Virology Beijing Pediatric Research Institute Beijing Children' s Hospital Capital Medical University National Center for Children's Health Beijing China.ORCID https://orcid.org/0000-0001-7634-9338

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Infectious mononucleosis (IM) and Kawasaki disease (KD) can present with overlapping clinical features, occasionally complicating the differential diagnosis. Given the significant differences in their management, accurate distinction is critical. It is exceptionally rare for a single patient to simultaneously suffer from both IM and KD in clinical practice. Case presentation: We report two cases of children over five years of age who initially presented with clinical manifestations suggestive of IM and serological evidence consistent with primary Epstein-Barr virus (EBV) infection, supporting an initial diagnosis of IM. Subsequently, both patients developed clinical features meeting the diagnostic criteria for KD. The final diagnosis was co-occurrence of IM and KD. Conclusion: We describe two cases of concurrent IM and KD, offering further insight into a possible association between primary EBV infection and KD. Clinicians should be mindful of the potential co-occurrence of these disorders, strive to avoid conflicts in treatment strategies, and take proactive measures to prevent complications.

Indexed as

DiagnosisEpstein‐Barr virus infectionInfectious mononucleosisKawasaki diseaseTreatment

Identifiers

PMID41426372
PMCPMC12715890

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.