Evidence map›Paper›PMID 41426969›Full record

ArticleSovremennye tekhnologii v meditsine2025

Genetic Scale for Predicting the No-Reflow Phenomenon in Myocardial Infarction.

I G Pochinka, A A Frolov, K V Kuzmichev, N A Shchelchkova, V I Pershin, N S Maximova, M L Budkina, I V Predeina, I A Frolov, M G Kashtanov

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Sovremennye tekhnologii v meditsine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05355532 (Identification of Genetic Determinants of the Coronary Microvascular Obstruction Development in Percutaneous Coronary Interventions), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05355532 completednot on this map

Identification of Genetic Determinants of the Coronary Microvascular Obstruction Development in Percutaneous Coronary Interventions

TypeobservationalSponsorPrivolzhsky Research Medical UniversityRan2022 to 2023Enrolled80ConditionsMyocardial Infarction, No-Reflow PhenomenonArmsdifferent variants of SNPs that may be associated with the coronary microvascular obstruction development
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. AnGlobal cardiology science & practice · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

I G PochinkaMD, DSc, Associate Professor, Head of the Department of Endocrinology and Internal Medicine; Privolzhsky Research Medical University, 10/1 Minin and Pozharsky Square, Nizhny Novgorod, 603005, Russia.
A A FrolovMD, PhD, Associate Professor, B.A. Korolev Department of Hospital Surgery; Privolzhsky Research Medical University, 10/1 Minin and Pozharsky Square, Nizhny Novgorod, 603005, Russia.
K V KuzmichevAssistant, Department of Endocrinology and Internal Medicine; Privolzhsky Research Medical University, 10/1 Minin and Pozharsky Square, Nizhny Novgorod, 603005, Russia.
N A ShchelchkovaPhD, Head of the Central Research Laboratory; Privolzhsky Research Medical University, 10/1 Minin and Pozharsky Square, Nizhny Novgorod, 603005, Russia.
V I PershinJunior Researcher, Molecular Genetics Department, Central Research Laboratory; Privolzhsky Research Medical University, 10/1 Minin and Pozharsky Square, Nizhny Novgorod, 603005, Russia.
N S MaximovaJunior Researcher, Molecular Genetics Department, Central Research Laboratory; Privolzhsky Research Medical University, 10/1 Minin and Pozharsky Square, Nizhny Novgorod, 603005, Russia.
M L BudkinaMD, PhD, Associate Professor, Department of Endocrinology and Internal Medicine; Privolzhsky Research Medical University, 10/1 Minin and Pozharsky Square, Nizhny Novgorod, 603005, Russia.
I V PredeinaBiologist, Genetic Diagnostics Laboratory, Center for Agrobiotechnology, Institute of Fundamental Medicine; Privolzhsky Research Medical University, 10/1 Minin and Pozharsky Square, Nizhny Novgorod, 603005, Russia.
I A FrolovPhysician, Department of X-ray Surgical Methods of Diagnosis and Treatment; City Clinical Hospital No.13 of the Avtozavodsky District of Nizhny Novgorod, 51 Patriotov St., Nizhny Novgorod, 603018, Russia.
M G KashtanovMD, PhD, Physician, Department of X-ray Surgical Methods of Diagnosis and Treatment; Regional Clinical Hospital No.1, 55 Kotovskogo St., Tyumen, 625023, Russia; Researcher, Laboratory of X-ray Surgical Methods of Diagnosis and Treatment; Ural Federal University named after the First President of Russia B.N. Yeltsin, 19 Mira St., Ekaterinburg, 620002, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Materials and Methods: A single-center matched case-control study was conducted. The study included 80 STEMI patients: 40 (50%) with no-reflow and 40 (50%) without no-reflow (1:1 matching by sex and age). No-reflow was defined as TIMI flow grade <3 or Myocardial blush grade <2 after PCI. The following SNPs were assessed: rs4961 ( Results: The following SNPs were associated with the development of the no-reflow phenomenon: rs4961 (genotype GT or TT) in the

Indexed as

Myocardial InfarctionNo-Reflow PhenomenonPercutaneous Coronary InterventionPolymorphism, Single NucleotideST Elevation Myocardial InfarctionAgedCase-Control StudiesFemaleHumansMaleMiddle Agedmyocardial infarctionno-reflow phenomenonpercutaneous coronary interventionsingle nucleotide polymorphism

Identifiers

PMID41426969
PMCPMC12715492

What Socratic holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.