Evidence map›Paper›PMID 41427426›Full record

ArticleRegenerative biomaterials2025

Magnesium ion hydrogel enhances resistance to radiation-induced bone injury by modulating the bone immune microenvironment and promoting microvascularization.

Qiong Wang, Xinpeng Hu, Zeyu Xiao, Kunlin Ye, Jia Li, Jiaxin Tan, Nuonuo Rao, Dong Zhang, Guodong Sun, Mingxiang Cai and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Regenerative biomaterials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Phenylethanoid Glycosides fromInternational journal of molecular sciences · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Qiong WangMedical Imaging Center, The First Affiliated Hospital of Jinan University, Guangzhou 510630, China.
Xinpeng HuThe Affiliated Dongguan Songshan Lake Central Hospital, Guangdong Medical University, Dongguan 523326, China.
Zeyu XiaoMedical Imaging Center, The First Affiliated Hospital of Jinan University, Guangzhou 510630, China.
Kunlin YeMedical Imaging Center, The First Affiliated Hospital of Jinan University, Guangzhou 510630, China.
Jia LiHospital of Stomatology, The First Affiliated Hospital of Jinan University, School of Stomatology, Jinan University, Guangzhou 510630, China.
Jiaxin TanHospital of Stomatology, The First Affiliated Hospital of Jinan University, School of Stomatology, Jinan University, Guangzhou 510630, China.
Nuonuo RaoHospital of Stomatology, The First Affiliated Hospital of Jinan University, School of Stomatology, Jinan University, Guangzhou 510630, China.
Dong ZhangMedical Imaging Center, The First Affiliated Hospital of Jinan University, Guangzhou 510630, China.
Guodong SunThe Fifth Affiliated Hospital (Heyuan Shenhe People's Hospital), Jinan University, Heyuan 517000, China.
Mingxiang CaiHospital of Stomatology, The First Affiliated Hospital of Jinan University, School of Stomatology, Jinan University, Guangzhou 510630, China.
Ni ShaoMedical Imaging Center, The First Affiliated Hospital of Jinan University, Guangzhou 510630, China.
Nianlan ChengMedical Imaging Center, The First Affiliated Hospital of Jinan University, Guangzhou 510630, China.
Le BaiMedical Imaging Center, The First Affiliated Hospital of Jinan University, Guangzhou 510630, China.
Xiangning LiuHospital of Stomatology, The First Affiliated Hospital of Jinan University, School of Stomatology, Jinan University, Guangzhou 510630, China.
Changzheng ShiMedical Imaging Center, The First Affiliated Hospital of Jinan University, Guangzhou 510630, China.
Liangping LuoMedical Imaging Center, The First Affiliated Hospital of Jinan University, Guangzhou 510630, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mandibular radiation-induced bone injury (RIBI) is a common, severe complication of radiotherapy with no effective treatment. The early course is clinically subtle yet pathologically complex: ionizing radiation (IR) rapidly induces microvascular dysfunction, amplifies immune-mediated inflammation and disrupts bone homeostasis. This complexity, together with safety considerations, hampers therapeutic translation. Magnesium (Mg

Indexed as

iron metabolismmagnesium ionsmicrovascularizationosteoimmunityradiation-induced bone injury

Identifiers

PMID41427426
PMCPMC12714384

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.