Evidence map›Paper›PMID 41428059›Full record

Trial reportEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026

Clinical impact of enhanced recovery after spinal surgery protocols on one-level lumbar arthrodesis: results from a single-center randomized controlled trial.

Ardavan Kashtiara, Jonah Pauptit, Dieter Thijs, Gino Verleye, Maxime Verstraeten, Peter Verelst, Charlotte Stolte, Erik Van de Kelft

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ardavan KashtiaraDepartment of Neurosurgery, VITAZ, Sint-Niklaas, Belgium. ardavan.kashtiara@vitaz.be.
Jonah PauptitFaculty of Medicine, Ghent University, Ghent, Belgium.
Dieter ThijsDepartment of Neurosurgery, VITAZ, Sint-Niklaas, Belgium.
Gino VerleyeFaculty of Political and SocialSciences, Ghent university, Ghent, Belgium.
Maxime VerstraetenDepartment of Anesthesiology, VITAZ, Sint-Niklaas, Belgium.
Peter VerelstDepartment of Anesthesiology, VITAZ, Sint-Niklaas, Belgium.
Charlotte StolteDepartment of Anesthesiology, VITAZ, Sint-Niklaas, Belgium.
Erik Van de KelftDepartment of Neurosurgery, VITAZ, Sint-Niklaas, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesEnhanced Recovery After Surgery (ERAS) protocols aim to improve surgical outcomes, by mitigating postoperative stress through multimodal perioperative care. In spinal surgery, such protocols may reduce pain, hospital length of stay (LoS), and opioid use. However, prior retrospective studies often suffer from heterogeneity in patient populations and surgical procedures, limiting interpretability. This trial was designed to evaluate the impact of an ERAS protocol on short-term clinical outcomes and LoS in patients undergoing elective single-level lumbar arthrodesis for degenerative spondylolisthesis.

methodsThis single center randomized controlled trial included 42 patients allocated to ERAS (n = 18) or standard care (n = 24). The ERAS protocol included preoperative Gabapentin administration, intraoperative multimodal analgesia, same-day physiotherapy, and early nutritional intake. The primary outcome was LoS. Secondary outcomes included pain at discharge, opioid consumption, postoperative complications, and unplanned readmissions occurring within 11 days after discharge. Data were analyzed using univariate statistical tests and multivariable regression models.

resultsMedian LoS was 3 days in both groups (p = .685). Pain scores at discharge were lower in the ERAS group (mean 2.5 ± 1.5) versus control (3.1 ± 2.2), though not statistically significant (p = .079). Multivariate analysis identified World Health Organization (WHO) pain medication level as a significant predictor of LoS (p = .025), and postoperative nausea and vomiting (PONV) as a predictor of discharge pain (p = .031). No significant differences were observed in complications or readmission rates.

conclusionERAS protocol did not reduce LoS in single level lumbar arthrodesis. Discharge pain and PONV had a significant impact on recovery, suggesting that these could be potential focal points for protocol refinement. Larger, procedure-specific trials with long-term follow-up are warranted.

Indexed as

ArthrodesisEnhanced Recovery After SurgeryLumbar VertebraeSpinal FusionSpondylolisthesisAgedAnalgesics, OpioidFemaleGabapentinHumansLength of StayMaleMiddle AgedPerioperative CarePostoperative PainTreatment OutcomeAnalgesics, OpioidGabapentinDegenerative spondylolisthesisEnhanced recovery after surgery (ERAS)Length of stayLumbar arthrodesisPostoperative pain

Identifiers

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.