Evidence map›Paper›PMID 41428467›Full record

SynthesisJournal of Alzheimer's disease : JAD2026

Individual sedentary activities and cognitive function in middle-aged and older adults: A systematic review.

Jiatong Chen, Kirsten Dillon-Rossiter, Lily Grigsby-Duffy, Anisa Morava, Adam Novic, Babac Salmani, Siobhan Smith, Harry Prapavessis, Paul A Gardiner

Abstract readSystematic Review
In one paragraph

Synthesis in Journal of Alzheimer's disease : JAD, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jiatong ChenThe University of Queensland, School of Public Health, Brisbane, Australia.
Kirsten Dillon-RossiterWestern University, London, Ontario, Canada.
Lily Grigsby-DuffyLung Foundation Australia, Brisbane, Australia.
Anisa MoravaWestern University, London, Ontario, Canada.
Adam NovicGriffith University, Brisbane, Australia.
Babac SalmaniWestern University, London, Ontario, Canada.
Siobhan SmithWestern University, London, Ontario, Canada.
Harry PrapavessisWestern University, London, Ontario, Canada.
Paul A GardinerThe University of Queensland, School of Public Health, Brisbane, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundThe influence of lifestyle factors on cognitive health, particularly among middle-aged and older adults, has garnered significant attention in gerontology and cognitive neuroscience. Currently, over 55 million people worldwide are living with dementia, including Alzheimer's disease with nearly 10 million new cases annually. Although sedentary behavior has been associated with cognitive decline, these studies often treat sitting time as a homogeneous entity, without considering the specific nature of sedentary activities.ObjectiveThis systematic review aims to examine associations of individual sitting activities with cognitive function in middle-aged and older adults.MethodsData were searched using eight electronic databases (EMBASE, Web of Science, PsycINFO, CINAHL, Medline, SPORTDiscus, PubMed, and Scopus) from inception to September 2024. Qualitative studies, reviews, conference abstracts, theses, and book chapters were excluded. The methodological quality of included studies was assessed using the QualSyst tool.ResultsA total of 85 studies (n = 1,575,657) were included in this review. Of the 43 studies examining television viewing, 28 (65%) reported a negative association between prolonged television viewing and cognitive function. Conversely, among the 58 studies that included active sedentary activities, only five (8.6%) reported negative associations.ConclusionsThe cognitive effects of sedentary behavior depend on the type of activity performed. Promoting cognitively engaging sedentary activities may support healthy cognitive aging, while excessive passive behaviors may increase risk of cognitive decline and Alzheimer's disease. Future research should focus on further clarifying the mechanisms behind these associations and explore interventions to enhance cognitive health in aging populations.

Indexed as

CognitionCognitive DysfunctionSedentary BehaviorAgedExerciseHumansMiddle AgedagingAlzheimer's diseasecognitioncognitive dysfunctionsedentary activitysedentary behavior

Identifiers

PMID41428467
PMCPMC12932704

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.