Evidence map›Paper›PMID 41432713›Full record

ArticleeLife2025

DendroTweaks, an interactive approach for unraveling dendritic dynamics.

Roman Makarov, Spyridon Chavlis, Panayiota Poirazi

Abstract read
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

  • Update of
    2025
5 · Who and what money

Authors and funding

3 authors.

Roman MakarovDepartment of Biology, University of Crete, Heraklion, Greece.ORCID https://orcid.org/0000-0002-4174-3826
Spyridon ChavlisInstitute of Molecular Biology and Biotechnology (IMBB), Foundation for Research and Technology-Hellas (FORTH), Heraklion, Greece.ORCID https://orcid.org/0000-0002-1046-1201
Panayiota PoiraziInstitute of Molecular Biology and Biotechnology (IMBB), Foundation for Research and Technology-Hellas (FORTH), Heraklion, Greece.ORCID https://orcid.org/0000-0001-6152-595X

Funding

Experimental and modeling investigations into microcircuit, cellular and subcellular determinants of hippocampal ensemble recruitment to contextual representationsR01MH124867 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LOSONCZY, ATTILA, POIRAZI, PANAYIOTA · 2021 to 2025
$3.4M
Hellenic Foundation for Research and Innovation - Stavros Niarchos Foundation GA-28056Horizon 2020 Framework Programme GA-860949Horizon 2020 Framework Programme GA-863245Horizon 2020 Framework Programme GA-873178NIH HHS 1R01MH124867NIMH NIH HHS R01 MH124867
6 · The paper itself

Abstract

Neurons rely on the interplay between two critical components, dendritic morphology and ion channels, to transform synaptic inputs into a sequence of somatic spikes. Detailed biophysical models with active dendrites have been instrumental in exploring this interaction. However, such models can be challenging to understand and validate due to the large number of parameters involved. In this work, we introduce

Indexed as

DendritesModels, NeurologicalNeuronsSoftwareAnimalsSynapsesactive dendritesbiophysical modelelectrophysiologyion channelsmorphologymouseneurosciencesingle neurontoolbox

Identifiers

PMID41432713
PMCPMC12726829

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.