Evidence map›Paper›PMID 41433304›Full record

ArticleInfection and immunity2026

Human body temperature cues widespread changes in virulence gene expression in uropathogenic

Carolyn A Dehner, Isidora N Stankovic, Madeleine Sutherland, Lou Ann Bierwert, Kalina P Dimova, Stylianos P Scordilis, Daniel M Stoebel, Christine A White-Ziegler

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection and immunity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Carolyn A DehnerDepartment of Biological Sciences and Program in Biochemistry, Smith College, Northampton, Massachusetts, USA.
Isidora N StankovicDepartment of Biological Sciences and Program in Biochemistry, Smith College, Northampton, Massachusetts, USA.
Madeleine SutherlandDepartment of Biological Sciences and Program in Biochemistry, Smith College, Northampton, Massachusetts, USA.
Lou Ann BierwertDepartment of Biological Sciences and Program in Biochemistry, Smith College, Northampton, Massachusetts, USA.
Kalina P DimovaDepartment of Biological Sciences and Program in Biochemistry, Smith College, Northampton, Massachusetts, USA.
Stylianos P ScordilisDepartment of Biological Sciences and Program in Biochemistry, Smith College, Northampton, Massachusetts, USA.
Daniel M StoebelDepartment of Biology, Harvey Mudd College, Claremont, California, USA.ORCID 0000-0002-9461-7567
Christine A White-ZieglerDepartment of Biological Sciences and Program in Biochemistry, Smith College, Northampton, Massachusetts, USA.ORCID 0009-0002-0756-9630

Funding

Short-term responses to temperature changes in Escherichia coliR15GM093908 · NIGMS · SMITH COLLEGE · PI WHITE-ZIEGLER, CHRISTINE A · 2010 to 2010
$392k
National Science Foundation 1716794NIGMS NIH HHS R15 GM093908NIH HHS 1R15GM93908-1
6 · The paper itself

Abstract

As a bacterial pathogen enters a human host, it immediately encounters a temperature upshift to 37°C. Mimicking the early hours of infection, we analyzed the transcriptome and proteome of uropathogenic

Indexed as

Gene Expression Regulation, BacterialUropathogenic Escherichia coliVirulence FactorsBiofilmsEscherichia coli InfectionsEscherichia coli ProteinsGene Expression ProfilingHumansProteomeTemperatureVirulenceEscherichia coli ProteinsProteomeVirulence Factorsadhesionbiofilmfimbriaeimmune evasionproteomeRpoSsRNAstress responsetemperaturetranscriptional regulationtranscriptomevirulence

Identifiers

PMID41433304
PMCPMC12890032

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.