ReviewJournal of oral & facial pain and headache2025
Burning mouth syndrome: updates on pathogenesis and diagnostic algorithms.
Review in Journal of oral & facial pain and headache, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Topical Pregabalin in Burning Mouth Syndrome: A Real-World Study of Peripheral Neuromodulation.Medicina (Kaunas, Lithuania) · 2026Article
- Topical Piperine for the Management of Burning Mouth Syndrome: A Case Series.Journal of clinical medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Burning Mouth Syndrome (BMS) is a complex, chronic neuropathic orofacial pain disorder characterized by a persistent burning or dysesthetic sensation in the oral cavity without an identifiable organic cause. Accurate diagnosis and effective management of BMS pose significant challenges to clinicians, necessitating a comprehensive and multidisciplinary approach. This review delves into BMS's pathogenesis and diagnostic algorithms, highlighting the latest advancements in understanding the underlying mechanisms and diagnostic strategies. Utilizing specific diagnostic algorithms assists clinicians in assessing and selecting appropriate treatment strategies, thereby minimizing diagnostic delays. These algorithms are crucial for excluding other causes of oral burning by focusing on symptomatology, patient history, and clinical examination. They involve ruling out oral infections, nutritional deficiencies, hormonal imbalances, autoimmune disorders, and medication side effects as potential causative factors. Supporting the diagnostic process, additional tests such as blood tests (including a thrombophilic panel and Neuron-Specific Enolase), neurosensory assessments, neuroradiological examinations, and evaluations of psychological profiles and cognitive function may be employed. Neurosensory assessments and neuroradiological examinations can provide insights into possible neuropathic causes, while psychological and cognitive assessments can identify any psychological factors and the extent to which cognitive decline may contribute to the condition. A comprehensive diagnostic approach not only aids in the accurate identification of BMS but also helps differentiate it from other oral conditions with similar presentations. This thorough evaluation is essential for developing a tailored treatment plan that addresses each patient's specific needs, ultimately improving clinical outcomes and enhancing the quality of life for individuals suffering from BMS.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.