Evidence map›Paper›PMID 41436736›Full record

Trial reportScientific reports2025

Personalisation of the Dutch combined lifestyle intervention SLIMMER improves participant retention and weight loss in people at risk for cardiometabolic disease.

Johanneke E Oosterman, Dagmar J Smid, Regina J M Kamstra, Iris M de Hoogh, Arjan H J Huizing, Martien P M Caspers, Tim J van den Broek, Robert Kleemann, Pepijn van Empelen, Josien Ter Beek and 2 more

Abstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Johanneke E Oosterman *Health and Work, Netherlands Organization for Applied Scientific Research (TNO), Leiden, The Netherlands.
Dagmar J Smid *Health and Work, Netherlands Organization for Applied Scientific Research (TNO), Leiden, The Netherlands.
Regina J M KamstraHealth and Work, Netherlands Organization for Applied Scientific Research (TNO), Leiden, The Netherlands.
Iris M de HooghHealth and Work, Netherlands Organization for Applied Scientific Research (TNO), Leiden, The Netherlands.
Arjan H J HuizingHealth and Work, Netherlands Organization for Applied Scientific Research (TNO), Leiden, The Netherlands.
Martien P M CaspersHealth and Work, Netherlands Organization for Applied Scientific Research (TNO), Leiden, The Netherlands.
Tim J van den BroekHealth and Work, Netherlands Organization for Applied Scientific Research (TNO), Leiden, The Netherlands.
Robert KleemannHealth and Work, Netherlands Organization for Applied Scientific Research (TNO), Leiden, The Netherlands.
Pepijn van EmpelenHealth and Work, Netherlands Organization for Applied Scientific Research (TNO), Leiden, The Netherlands.
Josien Ter BeekGGD Noord- and Oost-Gelderland (Community Health Service), Zutphen, The Netherlands.
Wilrike J PasmanHealth and Work, Netherlands Organization for Applied Scientific Research (TNO), Leiden, The Netherlands.
Suzan WopereisHealth and Work, Netherlands Organization for Applied Scientific Research (TNO), Leiden, The Netherlands. suzan.wopereis@tno.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Dutch combined lifestyle intervention (CLI) program SLIMMER is effective in changing lifestyle behaviour. However, achieving and maintaining a healthier lifestyle is difficult. Here, a personalised version of the SLIMMER CLI was evaluated for effects on lifestyle advice adherence as primary outcome and effects on weight loss, metabolism and inflammation as secondary outcomes. In this cluster-allocated controlled open-label parallel intervention study with 4 different health care sites per cluster, 61 participants in the personalised and 60 participants in the regular SLIMMER CLI (control) were included. Adults at risk for cardiometabolic disease were followed for 6 months. Adherence to lifestyle advice, Dutch Healthy Diet Index (DHDI), self-efficacy, lifestyle maintenance and quality of life (QoL) was assessed by questionnaires. Body composition and blood samples were measured at baseline and end of study. At 6 months the dropout rate was lower in the intervention group (11%) than in the control group (23%, p < 0.001). Self-reported adherence to lifestyle advice and DHDI improved in both groups at 3 and 6 months, whereas self-efficacy and lifestyle maintenance did not change as a result of the intervention. At 6 months self-reported adherence to physical activity guidelines and QoL was higher in favour of control. At 6 months, body weight (-4.5 kg, p = 0.006), BMI (-1.5 kg/m

Indexed as

Cardiovascular DiseasesLife StyleWeight LossAdultExerciseFemaleHumansMaleMiddle AgedNetherlandsQuality of LifeRisk Reduction BehaviorSelf EfficacyLifestyleObesityPrecision medicinePrimary health careRisk factorsWeight loss

Identifiers

PMID41436736
PMCPMC12727746

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.