Evidence map›Paper›PMID 41436940›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2026

Geographically structured genotypes and resistance clustering in Aspergillus fumigatus.

Won-Bok Kim, Dukhee Nho, Sung-Yeon Cho, Dong-Gun Lee, Chulmin Park, Raeseok Lee

Abstract read
In one paragraph

Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Deciphering the genomic landscape ofMicrobial genomics · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Won-Bok KimGenes Laboratories Inc, Yongin-si, Gyeonggi-do, Republic of Korea.ORCID http://orcid.org/0000-0002-9111-0365
Dukhee NhoDivision of Infectious Diseases, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.ORCID http://orcid.org/0000-0003-2800-636X
Sung-Yeon ChoDivision of Infectious Diseases, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.ORCID http://orcid.org/0000-0001-5392-3405
Dong-Gun LeeDivision of Infectious Diseases, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.ORCID http://orcid.org/0000-0003-4655-0641
Chulmin ParkVaccine Bio Research Institute, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.ORCID http://orcid.org/0000-0001-9147-0478
Raeseok LeeDivision of Infectious Diseases, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea. misozium03@catholic.ac.kr.ORCID http://orcid.org/0000-0002-1168-3666

Funding

Ministry of Education NRF-2022R1I1A1A01070887
6 · The paper itself

Abstract

We analysed 498 global Aspergillus fumigatus isolates using multilocus variable-number tandem-repeat (MLVA) typing to investigate regional clustering, environmental-clinical overlap, and azole resistance patterns. The dataset, which included 155 newly genotyped Korean strains, revealed extensive genotypic diversity and four distinct phylogeographic clusters. Resistance-associated mutations (TR34/TR46) appeared concentrated within certain clusters that largely comprised isolates from Germany, South Korea, and China, suggesting country-level enrichment rather than broader continental trends. These findings support the presence of geographically structured populations and localised emergence of resistance and demonstrate the utility of MLVA for molecular surveillance, particularly in settings where whole-genome sequencing is limited.

Indexed as

Antifungal AgentsAspergillosisAspergillus fumigatusDrug Resistance, FungalGenotypeAzolesChinaCluster AnalysisGenetic VariationHumansMicrobial Sensitivity TestsMinisatellite RepeatsPhylogeographyRepublic of KoreaAntifungal AgentsAzolesAntifungal resistanceAspergillus fumigatusEnvironmental microbiologyGeographic distributionMolecular epidemiology

Identifiers

PMID41436940
PMCPMC13086806

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.