ArticleInflammation2025
Deacetylasperulosidic Acid Methyl Ester Ameliorates Carbon Tetrachloride-Induced Liver Fibrosis by Suppressing Inflammation and Modulating Gut Microbiota.
Article in Inflammation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Ethyl Gallate Ameliorates High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease by Suppressing Inflammation and Modulating the Gut Microbiota-Intestinal Barrier Axis.Inflammation · 2026Article
- Dioscin in liver diseases: pharmacological mechanisms, translational potential and future perspectives.Frontiers in pharmacology · 2026Review
- Matrine in Liver Diseases: Mechanistic Insights and Therapeutic Potential.Drug design, development and therapy · 2026Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Liver fibrosis is an excessive wound-healing response triggered by chronic liver injury. It may eventually progress to cirrhosis, liver failure or liver cancer. Currently, there are no effective therapeutic strategies available. Deacetylasperulosidic acid methyl ester (DAM), a natural iridoid compound derived from Rubiaceae plants, possesses potential anti-inflammatory activity. However, its role in liver fibrosis and the underlying mechanisms remain unclear. Given the critical involvement of inflammation and gut microbiota dysbiosis in the development of liver fibrosis, this study aimed to investigate whether DAM could ameliorate liver fibrosis by modulating hepatic inflammation and intestinal dysbiosis. Using a carbon tetrachloride (CCl
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