Evidence map›Paper›PMID 41437519›Full record

ReviewCell transplantation

A narrative review of vascular conduits for coronary artery bypass grafting.

Georgina Iraola-Picornell, Elisabet Berastegui, Cristina Castells-Sala, Jordi Martorell, Antoni Bayes-Genis, Christian Muñoz-Guijosa, Carolina Gálvez-Montón

Abstract readReview
In one paragraph

Review in Cell transplantation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Georgina Iraola-PicornellICREC Research Lab, Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain.ORCID 0009-0004-8024-7210
Elisabet BerasteguiHeart Institute (iCOR), Germans Trias i Pujol University Hospital, Badalona, Spain.
Cristina Castells-SalaBlood and Tissue Bank (BST), Barcelona, Spain.ORCID 0000-0002-7520-5401
Jordi MartorellIQS School of Engineering, Universitat Ramon Llull (URL), Barcelona, Spain.
Antoni Bayes-GenisICREC Research Lab, Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain.
Christian Muñoz-GuijosaHeart Institute (iCOR), Germans Trias i Pujol University Hospital, Badalona, Spain.
Carolina Gálvez-MontónICREC Research Lab, Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronary artery bypass grafting (CABG) involves creating new conduits to restore blood flow to the heart. Using autologous vascular grafts presents challenges, including infection risk after vein harvesting, and scarcity of viable vein tissue. Researchers are exploring tissue-engineered vascular grafts (TEVGs), aiming to create optimal small-diameter vascular graft (SDVG) (<6 mm) for CABG surgery. TEVGs with suitable long-term patency could offer a promising alternative, potentially reduce patient morbidity and improve surgical outcomes. However, no SDVG is commercially available for CABG surgery in Europe, and no new clinical trials of coronary TEVGs have been reported since 2018. This narrative review summarizes the development and use of SDVG (<6 mm) for CABG, focusing on TEVGs and cell-seeding strategies. We outline the main types of grafts tested in preclinical and early clinical studies and highlight how different cell sources and seeding approaches aim to enhance graft functionality, patency, and long-term outcome.

Indexed as

Blood Vessel ProsthesisCoronary Artery BypassTissue EngineeringAnimalsHumanscell seedingclinical translation of TEVGcoronary artery bypass graftingcoronary artery diseasesmall-diameter conduitsstem cellstissue-engineered vascular grafts

Identifiers

PMID41437519
PMCPMC12745543

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.