ArticleAmerican journal of preventive cardiology2025
Trends in the prevalence of apparent treatment-resistant hypertension among U.S. adults, 1999-2018.
Article in American journal of preventive cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Prevalence of and associated factors for resistant hypertension in primary care settings: a systematic review and meta-analysis.BMC public health · 2026Pooled it
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aim: This study aimed to investigate the changing trends in the prevalence of apparent treatment-resistant hypertension (aTRH) in American adults between 1999 and 2018. Methods: We analyzed data from 50,906 non-pregnant individuals aged ≥20 years who participated in the National Health and Nutrition Examination Survey. Prevalence estimates were standardized by age and sex based on 2010 U.S. Census data. Results: Overall, the prevalence of aTRH remained relatively stable during the study period, ranging from 1.27 % to 1.33 %. However, significant differences existed between different sociodemographic subgroups. Higher prevalence was observed in older adults (≥65 years), women, non-Hispanic Black individuals, and those with lower levels of education level or family income. These differences may reflect age-related physiological changes, individual differences in drug response, genetic susceptibility, and the influence of structural social factors affecting health. Subgroup analysis showed that obesity, type 2 diabetes mellitus, cardiovascular diseases, and chronic kidney disease were all associated with a higher prevalence of aTRH. Conclusion: Our findings highlight the persistent burden of aTRH in specific high-risk populations and underscore the need for targeted, equity-oriented interventions to improve blood pressure control and reduce health disparities.
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