Correlation between cholesterol and ambulatory blood pressure in postmenopausal osteoporotic patients: a

Zebin Lin, Tianlong Wu, Yipin Zhao, Chizhen Wang, Gaofeng Wu

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Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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5 authors.

Zebin Lin *Department of Geriatrics, Xiamen Institute of Geriatric Rehabilitation, Zhongshan Hospital Affiliated to Xiamen University, Xiamen, China.

Tianlong Wu *Department of Geriatrics, Xiamen Institute of Geriatric Rehabilitation, Zhongshan Hospital Affiliated to Xiamen University, Xiamen, China.

Yipin ZhaoDepartment of Cardiology, Fuwai Central China Cardiovascular Hospital, Zhengzhou, China.

Chizhen WangDepartment of Geriatrics, Xiamen Institute of Geriatric Rehabilitation, Zhongshan Hospital Affiliated to Xiamen University, Xiamen, China.

Gaofeng WuDepartment of Geriatrics, Xiamen Institute of Geriatric Rehabilitation, Zhongshan Hospital Affiliated to Xiamen University, Xiamen, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To explore the correlation between cholesterol levels and 24-h dynamic blood pressure in postmenopausal women with osteoporosis. Methods: Ambulatory blood pressure monitoring was performed using a portable automated device, and cholesterol levels were measured using a fully automated biochemical analyzer. The relationship between cholesterol and blood pressure was analyzed using Shepherd's Pi correlation and generalized additive models (GAM) with piecewise linear regression to identify threshold effects. Results: The mean age of the participants was 73 years. Shepherd's Pi correlation analysis revealed a negative correlation between total cholesterol (TC) and intact parathyroid hormone (iPTH), as well as between high-density lipoprotein cholesterol (HDL-C) and Conclusion: A threshold effect exists between cholesterol and blood pressure in postmenopausal osteoporosis patients. Elevated TC and LDL-C beyond specific thresholds, as well as low HDL-C, are associated with higher blood pressure levels.

Indexed as

ambulatory blood pressurecholesterolhypertensionosteoporosispostmenopausal women

Identifiers

PMID41438142

DOI10.3389/fmed.2025.1662973

PMCPMC12719291

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