Evidence map›Paper›PMID 41438556›Full record

ReviewFood chemistry: X2025

Protein-polysaccharide composite design via molecular engineering: tailored fat mimetics for multifunctional food applications.

Anyi Zhang, Xiuping Liu, Xingdan Xia, Bei Yang, Wenjing Yan, Hao Dong, Wenzhen Liao, Xingfen Yang, Qi He

Abstract readReview
In one paragraph

Review in Food chemistry: X, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Anyi ZhangSchool of Public Health/Food Safety and Health Research Center/Guangdong Provincial Key Laboratory of Tropical Disease Research/BSL-3 Laboratory (Guangdong), Southern Medical University, Guangzhou 510515, China.
Xiuping LiuSchool of Public Health/Food Safety and Health Research Center/Guangdong Provincial Key Laboratory of Tropical Disease Research/BSL-3 Laboratory (Guangdong), Southern Medical University, Guangzhou 510515, China.
Xingdan XiaSchool of Public Health/Food Safety and Health Research Center/Guangdong Provincial Key Laboratory of Tropical Disease Research/BSL-3 Laboratory (Guangdong), Southern Medical University, Guangzhou 510515, China.
Bei YangSchool of Public Health/Food Safety and Health Research Center/Guangdong Provincial Key Laboratory of Tropical Disease Research/BSL-3 Laboratory (Guangdong), Southern Medical University, Guangzhou 510515, China.
Wenjing YanSchool of Public Health/Food Safety and Health Research Center/Guangdong Provincial Key Laboratory of Tropical Disease Research/BSL-3 Laboratory (Guangdong), Southern Medical University, Guangzhou 510515, China.
Hao DongCollege of Light Industry and Food Sciences, Zhongkai University of Agriculture and Engineering, Guangzhou 510225, China.
Wenzhen LiaoSchool of Public Health/Food Safety and Health Research Center/Guangdong Provincial Key Laboratory of Tropical Disease Research/BSL-3 Laboratory (Guangdong), Southern Medical University, Guangzhou 510515, China.
Xingfen YangSchool of Public Health/Food Safety and Health Research Center/Guangdong Provincial Key Laboratory of Tropical Disease Research/BSL-3 Laboratory (Guangdong), Southern Medical University, Guangzhou 510515, China.
Qi HeInstitute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dietary fat significantly contributes to the sensory properties of food. However, its excessive intake is strongly associated with obesity and related metabolic disorders. In response, protein-polysaccharide composites have emerged as promising fat mimetics capable of replicating the structural and sensory attributes of dietary fats. This review systematically elaborates a theoretical framework centered on multi-scale structural design, which integrates molecular interactions (covalent and non-covalent) with macro-scale fabrication strategies, such as micro/nano particles, hydrogels, oleogels, and emulsion gels, to tailor the physicochemical and sensory properties of fat substitutes. We emphasize that the rational manipulation of protein-polysaccharide interactions enables the mimicry of fat-related functionalities, including lubrication, texture, and flavor release. Although these systems show great potential in retaining desirable sensory characteristics, further validation in model food systems remains essential. Overall, this review offers a scientific roadmap for the development and application of protein-polysaccharide-based fat substitutes across diverse food matrices.

Indexed as

Fat substitutesFood structure designIntermolecular interactionsProtein-polysaccharide based composites

Identifiers

PMID41438556
PMCPMC12719207

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.