Evidence map›Paper›PMID 41438859›Full record

ArticleERJ open research2025

Association between asthma control and health-related quality of life in severe asthma: a cross-sectional study from KoSAR.

Noeul Kang, Seung-Eun Lee, Hyun Lee, Sang-Heon Kim, Woo-Jung Song, You Sook Cho, So-Young Park, Jae-Woo Jung, Hwa Young Lee, Han-Ki Park and 4 more

Abstract read
In one paragraph

Article in ERJ open research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Noeul KangDivision of Allergy, Department of Medicine, Samsung Medical Center, Sungkyunkwan University College of Medicine, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0003-0925-3891
Seung-Eun LeeDepartment of Internal Medicine, School of Medicine, Pusan National University, Pusan National University Yangsan Hospital, Yangsan, Republic of Korea.
Hyun LeeDivision of Pulmonary Medicine and Allergy, Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0002-1269-0913
Sang-Heon KimDivision of Pulmonary Medicine and Allergy, Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0001-8398-4444
Woo-Jung SongDepartment of Allergy and Clinical Immunology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0002-4630-9922
You Sook ChoDepartment of Allergy and Clinical Immunology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
So-Young ParkDepartment of Internal Medicine, Chung-Ang University Gwangmyeong hospital, Gwangmyeong, Republic of Korea.
Jae-Woo JungDepartment of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea.
Hwa Young LeeDivision of Allergy, Department of Internal Medicine, Seoul St Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Han-Ki ParkDivision of Allergy and Clinical Immunology, Department of Internal Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Chilgok Hospital, Daegu, Republic of Korea.ORCID https://orcid.org/0000-0002-5460-9917
Joo-Hee KimDepartment of Internal Medicine, Hallym University College of Medicine, Anyang, Republic of Korea.ORCID https://orcid.org/0000-0002-1572-5149
Ji-Su ShimDepartment of Internal Medicine, Ewha Womans University College of Medicine, Seoul, Republic of Korea.
Min-Hye KimDepartment of Internal Medicine, Ewha Womans University College of Medicine, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0002-1775-3733
Byung-Jae LeeDivision of Allergy, Department of Medicine, Samsung Medical Center, Sungkyunkwan University College of Medicine, Seoul, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Severe asthma (SA) imposes a significant burden on patients' health-related quality of life (HRQoL). This study aimed to quantify HRQoL burden and identify clinical determinants associated with HRQoL impairment in patients with SA. Methods: Cross-sectional data were collected from 701 patients (592 with SA, 109 with non-severe asthma (NSA)) in the Korean Severe Asthma Registry (KoSAR). HRQoL was measured using the EuroQoL 5-dimension 5-level (EQ-5D-5L) and Severe Asthma Questionnaire (SAQ). Asthma control status was assessed with the Asthma Control Test (ACT) scores. Multivariable and ordinal logistic regression analyses were conducted to identify factors associated with HRQoL. Results: Patients with SA had lower EQ-5D-5L scores than those with NSA (SA: 0.83 Conclusion: Uncontrolled asthma, particularly its impact on daily functioning, was associated with HRQoL impairment in patients with SA. Enhancing asthma control may significantly reduce the disease burden and improve HRQoL in SA.

Identifiers

PMID41438859
PMCPMC12720145

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.