ReviewCancer innovation2025
The Role of DNA Methyltransferases in Urinary System Diseases.
Review in Cancer innovation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- The Role of DNA Methyltransferases in Urinary System Diseases.Cancer innovation · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
DNA methylation is a crucial epigenetic regulatory mechanism that can modify chromatin structure, DNA conformation, DNA stability, and the interactions between DNA and proteins, thereby controlling gene expression. It has been shown to play a significant role in pathological processes such as fibrosis and tumorigenesis. DNA methyltransferases (DNMTs) are key players in this process. This study aims to investigate the role of DNMTs in the development of urinary system diseases, such as renal fibrosis and prostate cancer, revealing how they regulate gene expression by modulating DNA methylation levels, thereby significantly promoting the progression of these diseases. Additionally, this review explores their potential clinical applications as therapeutic targets, which may offer new research directions for understanding the pathogenesis and treatment of urinary system diseases in the future.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.