Evidence mapPaperPMID 41439617Full record

ArticleExperimental physiology2026

Effect of a single exercise bout on fasting cerebral blood flow and brain insulin sensitivity in middle-aged to older adults.

Steven K Malin, Ankit M Shah, Michal S Berri, David H Zald, Daniel J Battillo

Abstract read
In one paragraph

Article in Experimental physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Steven K MalinDepartment of Kinesiology and Health, Rutgers University, New Brunswick, New Jersey, USA.ORCID https://orcid.org/0000-0002-7360-6711
Ankit M ShahDepartment of Medicine, Division of Endocrinology, Metabolism and Nutrition, Rutgers University, New Brunswick, New Jersey, USA.
Michal S BerriInstitute for Health, Health Care Policy and Aging Research, Rutgers University, New Brunswick, New Jersey, USA.
David H ZaldCenter for Advanced Human Brain Imaging Research, Rutgers University, Piscataway, New Jersey, USA.
Daniel J BattilloDepartment of Kinesiology and Health, Rutgers University, New Brunswick, New Jersey, USA.

Funding

Brain Health Institute, Rutgers, The State University of New Jersey NANIH HHS R01DK133598-01A1
6 · The paper itself

Abstract

Reductions in brain insulin sensitivity and cerebral blood flow (CBF) have emerged as potential factors contributing to Alzheimer's disease and related dementia. However, no work has tested whether a single bout of exercise can raise brain insulin sensitivity in at-risk adults. The aim of the study was to test whether a single bout of exercise raises brain insulin sensitivity in middle-aged to older adults with cardiometabolic risk. In a counterbalanced pilot study design, 15 cognitively unimpaired (Montreal Cognitive Assessment, 28.2 ± 1.3 a.u.) adults [56.7 ± 2.1 years old; maximal oxygen consumption (

Indexed as

BrainCerebrovascular CirculationExerciseFastingInsulin ResistanceAgedBlood GlucoseFemaleHumansInsulinMaleMiddle AgedOxygen ConsumptionPilot ProjectsBlood GlucoseInsulincognitiondementiainsulin resistanceobesitytype 2 diabetes

Identifiers

PMID41439617
PMCPMC13140424

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.