Evidence map›Paper›PMID 41440255›Full record

ReviewBiosensors2025

Intelligent Biosensors Based on Hyaluronic Acid Hydrogels for Monitoring Chronic Wound Healing with the Involvement of Artificial Intelligence.

Antonia-Mihaela Nicolae, Mihaela Badea, Sandica Bucurica, Florina Rasaliu, Elena Mihaela Constantinescu

Abstract readReview
In one paragraph

Review in Biosensors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Antonia-Mihaela NicolaeDepartment of Fundamental, Prophylactic and Clinical Disciplines, Faculty of Medicine, Transilvania University of Brasov, 56 Nicolae Balcescu, 500019 Brasov, Romania.
Mihaela BadeaDepartment of Fundamental, Prophylactic and Clinical Disciplines, Faculty of Medicine, Transilvania University of Brasov, 56 Nicolae Balcescu, 500019 Brasov, Romania.ORCID 0000-0003-4824-2175
Sandica BucuricaFaculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bdul Eroilor Sanitari 8, 050474 Bucharest, Romania.ORCID 0000-0002-8787-3829
Florina RasaliuDepartment of Fundamental, Prophylactic and Clinical Disciplines, Faculty of Medicine, Transilvania University of Brasov, 56 Nicolae Balcescu, 500019 Brasov, Romania.
Elena Mihaela ConstantinescuDepartment of Fundamental, Prophylactic and Clinical Disciplines, Faculty of Medicine, Transilvania University of Brasov, 56 Nicolae Balcescu, 500019 Brasov, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic wounds, such as those caused by diabetes, burns, and pressure ulcers, pose significant healthcare challenges due to their slow healing and potential for infections. Traditional methods for monitoring wound healing are often intrusive, slow, and lack real-time data. To overcome these limitations, innovative biosensors using hyaluronic acid hydrogels have emerged as a promising solution. As a non-intrusive, biocompatible platform, these biosensors can track pH, glucose levels, inflammatory proteins, and other key biomarkers as wounds heal. With the integration of artificial intelligence (AI), they enable personalized treatment adjustments and early complication detection through real-time data analysis and predictive modeling. This review discusses the recent progress of hyaluronic acid hydrogel biosensors for long-term wound healing, evaluating their strengths, challenges, and potential future improvements. This work aims to enhance chronic wound management and improve multiple clinical outcomes by focusing on the intersection of biomaterial innovation and AI.

Indexed as

Artificial IntelligenceBiosensing TechniquesHyaluronic AcidHydrogelsWound HealingHumansHyaluronic AcidHydrogelsartificial intelligencebiomarkersbiosensorschronic wound healinghyaluronic acid hydrogels

Identifiers

PMID41440255
PMCPMC12730425

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.