Evidence map›Paper›PMID 41440281›Full record

ArticleBiosensors2025

Features of Chaperone Induction by 9-Aminoacridine and Acridine Orange.

Vadim V Fomin, Svetlana V Smirnova, Sergey V Bazhenov, Aminat G Kurkieva, Nikolay A Bondarev, Daria M Egorenkova, Daniil I Sakharov, Ilya V Manukhov, Serikbai K Abilev

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biosensors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Thermally InducedMicroorganisms · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Vadim V FominMoscow Center for Advanced Studies, Moscow 123592, Russia.ORCID 0000-0001-5090-8787
Svetlana V SmirnovaVavilov Institute of General Genetics, Russian Academy of Sciences, Moscow 119991, Russia.ORCID 0000-0002-8286-9345
Sergey V BazhenovMoscow Center for Advanced Studies, Moscow 123592, Russia.
Aminat G KurkievaVavilov Institute of General Genetics, Russian Academy of Sciences, Moscow 119991, Russia.
Nikolay A BondarevMoscow Center for Advanced Studies, Moscow 123592, Russia.ORCID 0000-0001-9230-5546
Daria M EgorenkovaMoscow Center for Advanced Studies, Moscow 123592, Russia.ORCID 0009-0000-2391-193X
Daniil I SakharovMoscow Center for Advanced Studies, Moscow 123592, Russia.
Ilya V ManukhovMoscow Center for Advanced Studies, Moscow 123592, Russia.
Serikbai K AbilevVavilov Institute of General Genetics, Russian Academy of Sciences, Moscow 119991, Russia.ORCID 0000-0001-8636-6828

Funding

Russian Science Foundation 22-14-00124-ПState Assignment 125091010190-9
6 · The paper itself

Abstract

The fluorescent dyes 9-aminoacridine (9-AA) and acridine orange (AO) are known mutagens that induce frameshift mutations in cells by intercalating between DNA bases. However, these chemicals can also affect other cellular components, such as proteins. In this study, we tested the ability of 9-AA and AO to induce heat shock in bacteria using the following methods: lux-biosensors based on

Indexed as

Acridine OrangeAminacrineBiosensing TechniquesMolecular ChaperonesEscherichia coliFluorescent DyesHeat-Shock ResponsePromoter Regions, GeneticAcridine OrangeAminacrineFluorescent DyesMolecular Chaperones9-aminoacridineacridine orangeheat shockluminescencelux-biosensor

Identifiers

PMID41440281
PMCPMC12730382

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.