Evidence map›Paper›PMID 41440666›Full record

ReviewJournal of fungi (Basel, Switzerland)2025

Silent Saboteurs: Decoding Mycotoxins-From Chemistry and Prevalence to Health Risks, Detection, Management and Emerging Frontiers.

Kasun M Thambugala, Dilakshini Dayananda, Samawansha Tennakoon, Hiruni Harischandra, Pamoda Jayatunga, Nissanka de Silva, Asanthi Dhanusha, Sahan Madusanka, Dinushani A Daranagama, Madhusha Gonapaladeniya and 2 more

Abstract readReview
In one paragraph

Review in Journal of fungi (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Aflatoxin exposure and health impacts: global burden and advances in detection technologies.Genes and environment : the official journal of the Japanese Environmental Mutagen Society · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Kasun M ThambugalaGenetics and Molecular Biology Unit, Faculty of Applied Sciences, University of Sri Jayewardenepura, Nugegoda 10250, Sri Lanka.ORCID 0000-0002-6210-0504
Dilakshini DayanandaGenetics and Molecular Biology Unit, Faculty of Applied Sciences, University of Sri Jayewardenepura, Nugegoda 10250, Sri Lanka.ORCID 0000-0003-3472-7251
Samawansha TennakoonGenetics and Molecular Biology Unit, Faculty of Applied Sciences, University of Sri Jayewardenepura, Nugegoda 10250, Sri Lanka.
Hiruni HarischandraGenetics and Molecular Biology Unit, Faculty of Applied Sciences, University of Sri Jayewardenepura, Nugegoda 10250, Sri Lanka.ORCID 0000-0003-3079-668X
Pamoda JayatungaGenetics and Molecular Biology Unit, Faculty of Applied Sciences, University of Sri Jayewardenepura, Nugegoda 10250, Sri Lanka.ORCID 0000-0002-7562-4294
Nissanka de SilvaGenetics and Molecular Biology Unit, Faculty of Applied Sciences, University of Sri Jayewardenepura, Nugegoda 10250, Sri Lanka.
Asanthi DhanushaGenetics and Molecular Biology Unit, Faculty of Applied Sciences, University of Sri Jayewardenepura, Nugegoda 10250, Sri Lanka.
Sahan MadusankaGenetics and Molecular Biology Unit, Faculty of Applied Sciences, University of Sri Jayewardenepura, Nugegoda 10250, Sri Lanka.
Dinushani A DaranagamaDepartment of Plant and Molecular Biology, Faculty of Science, University of Kelaniya, Kelaniya 11300, Sri Lanka.ORCID 0000-0001-5704-8943
Madhusha GonapaladeniyaDepartment of Medical Laboratory Sciences, Faculty of Allied Health Sciences, University of Sri Jayewardenepura, Nugegoda 10250, Sri Lanka.ORCID 0000-0002-4501-1198
Sukanya HaitukOffice of the Research Administration, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0001-9982-5202
Ratchadawan CheewangkoonDepartment of Entomology and Plant Pathology, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0001-8576-3696

Funding

National Science, Research and Innovation Fund (NSRF), Thailand. 4773818
6 · The paper itself

Abstract

Mycotoxins, toxic secondary metabolites produced by filamentous fungi, pose significant threats to global food safety, public health, and agricultural sustainability. This review summarizes the classification, biosynthesis, chemistry, and mechanisms of action of these compounds, and highlights their global prevalence and the serious health consequences of both acute and chronic exposure. Despite decades of research, substantial gaps remain in effective surveillance, prevention, and risk management. Traditional control and detection strategies, although valuable, are often limited by their sensitivity, high costs, and inadequate field applicability. Addressing these gaps, this review emphasizes the potential of emerging technologies, particularly the integration of artificial intelligence (AI) and machine learning (ML) with advanced sensing platforms, to revolutionize mycotoxin detection. These innovations offer enhanced precision, real-time monitoring, and predictive modelling capabilities, paving the way for proactive food safety systems. By critically evaluating current knowledge and exploring future-oriented solutions, this review highlights the urgent need for interdisciplinary approaches that integrate molecular insights, biotechnological advancements, and digital technologies. Finally, we emphasize that adopting these novel strategies is essential to overcoming the silent yet profound global impact of mycotoxins.

Indexed as

biosynthesis pathwaysfood safetyfungal metabolitesmachine learningmycotoxinsrisk assessment

Identifiers

PMID41440666
PMCPMC12734026

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.