ArticleJournal of cardiovascular development and disease2025
Females and Exercise Capacity Impairment in Heart Failure: A Sex-Focused Analysis.
Ainhoa Lorenzo, Raúl Ramos-Polo, Laia Lorenzo-Esteller, Xinying Lin, Emma Barragan, Paula Aranda, Èlia Boixader, Foix Regull, Nerea Martín, Ariana Ollé and 5 more
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In one paragraphArticle in Journal of cardiovascular development and disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 · Who and what moneyAuthors and funding
15 authors.
Ainhoa LorenzoBio-Heart Cardiovascular Diseases Research Group, Bellvitge Biomedical Research Institute (IDIBELL), 08907 Barcelona, Spain.ORCID 0009-0003-9900-0579 Raúl Ramos-PoloBio-Heart Cardiovascular Diseases Research Group, Bellvitge Biomedical Research Institute (IDIBELL), 08907 Barcelona, Spain.ORCID 0000-0001-7475-4145 Laia Lorenzo-EstellerBio-Heart Cardiovascular Diseases Research Group, Bellvitge Biomedical Research Institute (IDIBELL), 08907 Barcelona, Spain.ORCID 0000-0002-0066-0573 Xinying LinBio-Heart Cardiovascular Diseases Research Group, Bellvitge Biomedical Research Institute (IDIBELL), 08907 Barcelona, Spain.
Emma BarraganBio-Heart Cardiovascular Diseases Research Group, Bellvitge Biomedical Research Institute (IDIBELL), 08907 Barcelona, Spain.
Paula ArandaBio-Heart Cardiovascular Diseases Research Group, Bellvitge Biomedical Research Institute (IDIBELL), 08907 Barcelona, Spain.
Èlia BoixaderBio-Heart Cardiovascular Diseases Research Group, Bellvitge Biomedical Research Institute (IDIBELL), 08907 Barcelona, Spain.ORCID 0009-0001-3076-1308 Foix RegullBio-Heart Cardiovascular Diseases Research Group, Bellvitge Biomedical Research Institute (IDIBELL), 08907 Barcelona, Spain.
Nerea MartínBio-Heart Cardiovascular Diseases Research Group, Bellvitge Biomedical Research Institute (IDIBELL), 08907 Barcelona, Spain.
Ariana OlléBio-Heart Cardiovascular Diseases Research Group, Bellvitge Biomedical Research Institute (IDIBELL), 08907 Barcelona, Spain.
Marc LlagosteraBio-Heart Cardiovascular Diseases Research Group, Bellvitge Biomedical Research Institute (IDIBELL), 08907 Barcelona, Spain.
Núria José-BazánBio-Heart Cardiovascular Diseases Research Group, Bellvitge Biomedical Research Institute (IDIBELL), 08907 Barcelona, Spain.
Pedro MolinerBio-Heart Cardiovascular Diseases Research Group, Bellvitge Biomedical Research Institute (IDIBELL), 08907 Barcelona, Spain.ORCID 0000-0002-5511-8597 Cristina EnjuanesBio-Heart Cardiovascular Diseases Research Group, Bellvitge Biomedical Research Institute (IDIBELL), 08907 Barcelona, Spain.
Josep Comin-ColetBio-Heart Cardiovascular Diseases Research Group, Bellvitge Biomedical Research Institute (IDIBELL), 08907 Barcelona, Spain.ORCID 0000-0001-8780-720X Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
Heart failure (HF) is becoming increasingly common, especially in older females, and displays marked sex-related differences in pathophysiology, treatment, and outcomes. Submaximal exercise capacity (SEC), frequently measured by the six-minute walk test (6MWT), is an important marker of aerobic function, prognosis, and quality of life in HF. However, evidence regarding sex differences in SEC remains limited and inconsistent. This single-centre, prospective cohort study included 1069 patients with chronic HF enrolled between 2004 and 2014. SEC was assessed using the 6MWT, and extensive clinical and psychosocial data were collected. Multivariate models evaluated the independent association between sex and SEC. Results showed that females had significantly shorter 6MWT distances (155 ± 149 m) than males (265 ± 164 m;
Indexed as
evidence-based healthcareexercise toleranceheart failurequality of lifesex
Identifiers
PMID41440873
PMCPMC12733852
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