Evidence mapPaperPMID 41440909Full record

ArticleMarine drugs2025

Integrative Metabolomics, Pharmacoinformatics and Experimental Studies Reveal the Neuroprotective Potential of

Nita Handayani, Dhecella Winy Cintya Ningrum, Adha Fauzi Hendrawan, Anis Yuniati, Raffaele Romano, Lucia De Luca, Antonello Santini, Fahrul Nurkolis

Abstract read
In one paragraph

Article in Marine drugs, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nita HandayaniDepartment of Physics, Faculty of Science and Technology, Universitas Islam Negeri (UIN) Sunan Kalijaga Yogyakarta, Yogyakarta 55281, Indonesia.
Dhecella Winy Cintya NingrumMaster's Program in Pharmaceutical Science, Faculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta 55281, Indonesia.ORCID 0000-0002-4162-2151
Adha Fauzi HendrawanDepartment of Medicine, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Yogyakarta 55281, Indonesia.ORCID 0009-0004-9222-1173
Anis YuniatiDepartment of Physics, Faculty of Science and Technology, Universitas Islam Negeri (UIN) Sunan Kalijaga Yogyakarta, Yogyakarta 55281, Indonesia.
Raffaele RomanoDepartment of Agricultural Sciences, University of Napoli Federico II, Piazza Carlo di Borbone 1, 80055 Portici, NA, Italy.
Lucia De LucaDepartment of Agricultural Sciences, University of Napoli Federico II, Piazza Carlo di Borbone 1, 80055 Portici, NA, Italy.ORCID 0000-0002-2287-3633
Antonello SantiniDepartment of Pharmacy, University of Napoli Federico II, Via Domenico Montesano 49, 80131 Napoli, Italy.ORCID 0000-0001-5505-3327
Fahrul NurkolisMaster of Basic Medical Science, Faculty of Medicine, Universitas Airlangga, Surabaya 60286, Indonesia.ORCID 0000-0003-2151-0854

Funding

Penelitian Inovasi Teknologi Program of UIN Sunan Kalijaga Yogyakarta 3268.5.1/Un.02/PPK.3/TL/07/2025
6 · The paper itself

Abstract

Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder characterized by cholinergic dysfunction, oxidative/nitrosative stress, and neuroinflammation. Marine green algae

Indexed as

Alzheimer DiseaseCaulerpaNeuroprotective AgentsAcetylcholinesteraseAntioxidantsCholinesterase InhibitorsHumansMetabolomicsMolecular Docking SimulationNetwork PharmacologyPlant ExtractsAcetylcholinesteraseAntioxidantsCholinesterase InhibitorsNeuroprotective AgentsPlant ExtractsacetylcholinesteraseAlzheimer’s diseaseantioxidant activityCaulerpa racemosamarine functional foodmetabolomicsmolecular dockingnetwork pharmacologyneuroinflammationnitric oxide synthase

Identifiers

PMID41440909
PMCPMC12734677

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.