Evidence map›Paper›PMID 41440942›Full record

ArticleJournal of personalized medicine2025

Pharmacoepigenomics in Personalized Medicine: A Hypothesis-Generating Approach to Introduce CpG-PGx SNPs as New Candidates for a Systematic Insight into Genomic-Epigenomic-Phenomic-Pharmacogenomics (G-E-Ph-PGx) Axis.

Alireza Sharafshah, Kenneth Blum, Kai-Uwe Lewandrowski, Igor Elman, Brian S Fuehrlein, David Baron, Albert Pinhasov, Panayotis K Thanos, Rossano Kepler Alvim Fiorelli, Sergio L Schmidt and 4 more

Abstract read
In one paragraph

Article in Journal of personalized medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Alireza SharafshahCellular and Molecular Research Center, School of Medicine, Guilan University of Medical Sciences, Rasht 4144666949, Iran.ORCID 0000-0001-8048-9587
Kenneth BlumThe Kenneth Blum Behavioral & Neurogenetic Institute, Austin, TX 78701, USA.ORCID 0000-0001-6727-803X
Kai-Uwe LewandrowskiThe Kenneth Blum Behavioral & Neurogenetic Institute, Austin, TX 78701, USA.ORCID 0000-0001-7842-2914
Igor ElmanDepartment of Molecular Biology, Adelson School of Medicine, Ariel University, Ariel 40700, Israel.
Brian S FuehrleinDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT 06511, USA.ORCID 0000-0002-3202-8089
David BaronThe Kenneth Blum Behavioral & Neurogenetic Institute, Austin, TX 78701, USA.
Albert PinhasovDepartment of Molecular Biology, Adelson School of Medicine, Ariel University, Ariel 40700, Israel.
Panayotis K ThanosDepartment of Molecular Biology, Adelson School of Medicine, Ariel University, Ariel 40700, Israel.
Rossano Kepler Alvim FiorelliPrograma de Pós-Graduação em Neurologia, Universidade Federal do Estado do Rio de Janeiro, Rio de Janeiro 20270-004, Brazil.ORCID 0000-0001-5236-0903
Sergio L SchmidtPrograma de Pós-Graduação em Neurologia, Universidade Federal do Estado do Rio de Janeiro, Rio de Janeiro 20270-004, Brazil.ORCID 0000-0001-7654-5507
Eliot L GardnerNeuropsychopharmacology Section, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD 20892, USA.
Morgan P LorioAdvanced Orthopedics, 499 E. Central Pkwy, Ste. 130, Altamonte Springs, FL 32701, USA.ORCID 0009-0008-0619-1799
Alexander P L LewandrowskiDepartment of Biological Sciences, Dornsife College of Letters, Arts and Sciences, 3616 Trousdale Pkwy, Los Angeles, CA 90089, USA.
Mark S GoldDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110, USA.

Funding

Prenatal Tobacco and Cannabis Exposure: A Translational StudyR33DA045640 · NIDA · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI EIDEN, RINA D, THANOS, PANAYOTIS K · 2021 to 2023
$999k
Prenatal Tobacco and Cannabis Exposure: A Translational StudyR21DA045640 · NIDA · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI EIDEN, RINA D, THANOS, PANAYOTIS K · 2018 to 2019
$434k
A Systematic Medical Approach to Reward Transformation (SMART) for Brain Health in Opioid Use DisorderR41MD012318 · NIMHD · VERSA INTEGRATED SOLUTIONS, INC. · PI BLUM, KENNETH, GONDRE-LEWIS, MARJORIE C · 2017 to 2017
$221k
CSRD VA I01 CX000479CSRD VA I01 CX002099NIDA NIH HHS R21 DA045640NIDA NIH HHS R33 DA045640NIMHD NIH HHS R41 MD012318
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CpG-PGx SNPCpG siteCYP2D6PharmacoepigenomicsTET2

Identifiers

PMID41440942
PMCPMC12734362

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.